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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(8): 231-236
DOI: https://doi.org/10.20546/ijcmas.2020.908.026


Johne’s Disease in Domestic Animals and its Zoonotic Significance: A Review Article
Yash Bhargava1, Sushant Sharma2, Amit Singh Vishen3*,Jagnoor Singh Sandhu4 and Abhishek Mishra5
1Division of Parasitology, Sher-E-Kashmir University of Agricultural Sciences & Technology of Jammu, Jammu & Kashmir, India
2Veterinary officer polyclinic, Dholpur, Rajasthan, India
3Department of Veterinary Anatomy, C. V. Sc. & A. H., Acharya Narendra Dev University of Agriculture & Technology, Ayodhya, U.P., India
4Faculty of Veterinary Sciences & Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences & Technology of Jammu, Jammu & Kashmir, India
5College of Veterinary Sciences & Animal Husbandry, DUVASU, Mathura, India
*Corresponding author
Abstract:

Johne’s disease is a fatal gastrointestinal disease of ruminants and is caused by the Mycobacterium avium paratuberculosis (MAP). It is a zoonotic disease and in humans transmits as Crohn’s disease. The main clinical symptoms of Johne’s disease in ruminants are Severe diarrhoea with the increased thirst, progressive cachexia, emaciation, body coat is rough and hide bound condition. Humans can be exposed to the MAP through the consumption of raw milk of the infected dairy-herd with the pathogen, ground beef from the infected buffalo, domestic water supply which is originating from the surface source near the runoff from infected farms and improper pasteurization of milk. The large intestinal mucosa becomes cobble stone appearance in Crohn’s disease though it is corrugated in the JD. The treatment of this disease is not advocated but the vaccination could be done with heat killed or modified live preparation of Mycobacterium avium paratuberculosis strain-18. There should be maintenance of personal hygiene and use of boots, hand gloves and caps during handling of the animals.


Keywords: Johne’s, Crohn’s disease, Zoonosis and ruminants
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How to cite this article:

Yash Bhargava, Sushant Sharma, Amit Singh Vishen, Jagnoor Singh Sandhu and Abhishek Mishra. 2020. Johne’s Disease in Domestic Animals and its Zoonotic Significance: A Review ArticleInt.J.Curr.Microbiol.App.Sci. 9(8): 231-236. doi: https://doi.org/10.20546/ijcmas.2020.908.026