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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(7): 672-677
DOI: https://doi.org/10.20546/ijcmas.2020.907.077


Evaluation of Laboratory Methods to Measure Telomere Length in Cancer
Vikas Kumar Bhari1, Shreya Sharma1, Durgesh Kumar2, Surendra Kumar3, Abhijeet Singh1 and Rajeev Mishra1*
1Department of Biosciences, Manipal University Jaipur, Rajasthan, India
2Department of Physiology, Government Medical College, Kannauj, Uttar Pradesh, India
3Department of Neurology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India
*Corresponding author
Abstract:

Telomere comprises of TTAGGG repeats and its lack of functionality results in promoting cancer through driving genetic instability. It is evident that they protect chromosomal ends and conserve our genetic information. This review discusses various laboratory methods of telomere length measurement. Understanding more about how these methods work and can be modified, they can be universalized in terms of their use all over the globe. Regardless of whether telomere length quantification has a direct or indirect association with cancer progression/ prevention, its assessment has been shown to hold promise for better prognosis and reliable biomarker which allow the better assessment in early identification and therapeutic responses.


Keywords: Telomere, Biomarker, FISH, qPCR
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How to cite this article:

Vikas Kumar Bhari, Shreya Sharma, Durgesh Kumar, Surendra Kumar, Abhijeet Singh and Rajeev Mishra. 2020. Evaluation of Laboratory Methods to Measure Telomere Length in Cancer.Int.J.Curr.Microbiol.App.Sci. 9(7): 672-677. doi: https://doi.org/10.20546/ijcmas.2020.907.077