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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(7): 545-550
DOI: https://doi.org/10.20546/ijcmas.2020.907.060


Spectrum of Aetiological Agents of Endophthalmitis and Antimicrobial Resistance Pattern of Bacterial Isolates
Sukhjinder Singh, Loveena Oberoi*, Karamjit Singh, Sapna Soneja and Anuradha Malhotra
Department of Microbiology, Government Medical College, Amritsar, Baba Farld University of Health Sciences, Punjab, India
*Corresponding author
Abstract:

Eye is a complex and sensitive organ and is therefore more vulnerable to trauma and various infections. Indian population is vulnerable to infections of eye by virtue of subtropical climate, trauma and iatrogenic procedures. Infectious endophthalmitis is a threatening and potentially devastating intra‑ocular infection caused by an array of organisms. Exogenous endophthalmitis is an infective complication of primary cataract, intraocular surgery and ocular trauma due to the introduction of infectious pathogens like bacteria and fungi, whereas the endogenous one is commonly due to systemic dissemination of the pathogens. To isolate and identify bacteria and fungi from various ocular specimens and to study antimicrobial resistance pattern of aerobic bacterial pathogens isolated. The present prospective study was carried out from July 2018 to August 2019 in the Department of Microbiology of Government Medical College, Amritsar. Vitreous humor samples received from the Department of Ophthalmology of Government Medical College, Amritsar were processed and bacterial and fungal isolates were identified using standard microbiological procedures. Antimicrobial susceptibility testing of bacterial isolates was performed as per the latest CLSI guidelines. Out of the 54 vitrous humor specimens processed 25(43.1%) were positive on culture. Amongst bacteria, Staphylococcus epidermidis (36.8%) was the most predominant isolate, followed by Pseudomonas aeruginosa (26.3%). Highest resistance was observed to fluoroquinolones followed by cephalosporins. No isolates showed resistance to Vancomycin or Imipenem. Amongst the fungi Aspergillus flavus (62.5%) was the most common isolate followed by Candida albicans (25%) cases. Mixed bacterial and fungal growth was obtained from 2 specimens. Our study highlights the importance of various etiological agents causig endophthalmitis with their antimicrobial resistance patterns. High prevalence of bacterial infections necessitates religious adherence to the standardised protocols can prevent and provide better treatment for this dreaded intraocular complication.


Keywords: Infections of eye, subtropical climate, vitreous humor
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How to cite this article:

Sukhjinder Singh, Loveena Oberoi, Karamjit Singh, Sapna Soneja and Anuradha Malhotra. 2020. Spectrum of Aetiological Agents of Endophthalmitis and Antimicrobial Resistance Pattern of Bacterial Isolates.Int.J.Curr.Microbiol.App.Sci. 9(7): 545-550. doi: https://doi.org/10.20546/ijcmas.2020.907.060