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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(6): 3266-3279
DOI: https://doi.org/10.20546/ijcmas.2020.906.390


Biochemical Studies on Adverse Health Effects of Arsenic and Chromium in Buffaloes
Himalaya Bhardwaj*, Chanchal Singh and Shashi Nayyar
Department of Veterinary Biochemistry, Guru AngadDev Veterinary and Animal Sciences University, Ludhiana, Punjab, India-141004
*Corresponding author
Abstract:

The present study was undertaken to assess the damage caused by heavy metals, arsenic and chromium in slaughtered buffaloes. The assessment of adverse effects of these heavy metals in tissues (Liver, kidney, pancreas, and ovary) and blood have been determined by the expression of metallothionein, antioxidants and biochemical parameters. Tissue and blood samples were collected from buffaloes (n=50) from local abattoir to assess the level of arsenic and chromium. The concentration of these heavy metals was found to be significantly (p<0.05) higher in exposed group as compared to the control group. Malonldialdehyde (MDA) level in tissues and blood of each arsenic and chromium exposed groups were significantly (p<0.05) higher than the non-exposed control group. The activity of superoxide dismutase (SOD) and catalase (CAT) was found to be significantly increased (p<0.05) in tissues and blood of exposed group. The exposed buffaloes were found to have significantly (p<0.05) increased glucose, cholesterol, AST, LDH, CK, ALP, urea, and creatinine level as compared to control group. The fold change expression level of metal binding protein metallothionein (MT-2) in the heavy metal exposed tissues and blood was found to be variable expressed. liver and pancreas had maximum and minimum fold change MT-2 expression respectively. The study concluded that arsenic and chromium exposure in buffaloes could result in oxidative damage and alterations in the expression of metallothionein.


Keywords: Arsenic, Buffalo, Chromium, LDH, Metallothionein
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How to cite this article:

Himalaya Bhardwaj, Chanchal Singh and Shashi Nayyar. 2020. Biochemical Studies on Adverse Health Effects of Arsenic and Chromium in Buffaloes.Int.J.Curr.Microbiol.App.Sci. 9(6): 3266-3279. doi: https://doi.org/10.20546/ijcmas.2020.906.390