National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was undertaken to assess the damage caused by heavy metals, arsenic and chromium in slaughtered buffaloes. The assessment of adverse effects of these heavy metals in tissues (Liver, kidney, pancreas, and ovary) and blood have been determined by the expression of metallothionein, antioxidants and biochemical parameters. Tissue and blood samples were collected from buffaloes (n=50) from local abattoir to assess the level of arsenic and chromium. The concentration of these heavy metals was found to be significantly (p<0.05) higher in exposed group as compared to the control group. Malonldialdehyde (MDA) level in tissues and blood of each arsenic and chromium exposed groups were significantly (p<0.05) higher than the non-exposed control group. The activity of superoxide dismutase (SOD) and catalase (CAT) was found to be significantly increased (p<0.05) in tissues and blood of exposed group. The exposed buffaloes were found to have significantly (p<0.05) increased glucose, cholesterol, AST, LDH, CK, ALP, urea, and creatinine level as compared to control group. The fold change expression level of metal binding protein metallothionein (MT-2) in the heavy metal exposed tissues and blood was found to be variable expressed. liver and pancreas had maximum and minimum fold change MT-2 expression respectively. The study concluded that arsenic and chromium exposure in buffaloes could result in oxidative damage and alterations in the expression of metallothionein.
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