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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(5): 2299-2305
DOI: https://doi.org/10.20546/ijcmas.2020.905.262


Pseudomonas aeruginosa in Otitis Media: Prevalence and Antimicrobial Susceptibility Pattern in a Tertiary Care Hospital in India
Swati Mittal, Ravi Kumar Tiwary*, Amandeep Kaur, Rishabh Garg, Sonia Mittal and Arup Pegu
Department of Microbiology, Adesh Medical College & Hospital, NH-1, Vill- Mohri, Tehsil-Shahbad (M), Dist-Kurukshetra, Haryana-136135, India
*Corresponding author
Abstract:

Otitis media is an inflammation of the middle ear and mastoid cavity, with recurrent ear discharge through a perforated tympanic membrane. Pseudomonas aeruginosa has been particularly blamed for deep seated and progressive destruction of middle ear structures through its toxins and enzymes. The present study was done to determine the prevalence and antibiotic susceptibility of Pseudomonas aeruginosa isolated from otitis media. Patients fulfilling clinical criteria were considered into the study. Two ear swabs were taken from each patient. Sample processing and identification of organisms was done by standard bacteriological methods as per CLSI guidelines. Antimicrobial susceptibility was done by Kirby Bauer Disk diffusion method with 12 different antibiotics for Pseudomonas aeruginosa strains. Out of 131 samples, 110 (83.97%) has shown growth of significant pathogens. Pseudomonas aeruginosa strains were isolated from 45 (38.46%) samples. The resultsof antimicrobial susceptibility testing showed maximum sensitivity to Colistin, Imipenem and Polymyxin B (100%), followed by Aztreonam (95.56%), Piperacillin-Tazobactam (93.33%), Amikacin, Ceftazidime, Cefipime, Cefaperazone-Sulbactam (84.44%), Ciprofloxacin (82.22%), Gentamicin (80%) and Levofloxacin (68.89%). Knowing the etiological agents of otitis media and their antibiotic susceptibility is of paramount importance for an efficient treatment and prevention of both disease complications and antimicrobial resistance.


Keywords: Otitis media, Pseudomonas aeruginosa, Antimicrobial susceptibility testing, Kirby Bauer Disk diffusion, Antimicrobial resistance
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How to cite this article:

Swati Mittal, Ravi Kumar Tiwary, Amandeep Kaur, Rishabh Garg, Sonia Mittal and Arup Pegu. 2020. Pseudomonas aeruginosa in Otitis Media: Prevalence and Antimicrobial Susceptibility Pattern in a Tertiary Care Hospital in India.Int.J.Curr.Microbiol.App.Sci. 9(5): 2299-2305. doi: https://doi.org/10.20546/ijcmas.2020.905.262