National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary Tract Infections (UTI) account for more than 7 million visit for outpatient consultation. UTI is the second commonest one, after the Respiratory Tract Infection. Prevalence in young women is 30 times more than in men. The prevalence of bacteriuria increases with hospitalization and concurrent diseases. UTI types of complicated, uncomplicated, nosocomial UTI, and especially Uropathogenic Escherichia coli (UPEC) are some of important ones. The main aim of the study include to find the prevalence of uropathogenic E.coli Strains – UPEC at a Tertiary Care Centre; To Characterize the virulence factors of Uropathogens; To evaluate bacterial isolates contributing to the uropathogens, and its virulence factors; To study the antimicrobial susceptibility pattern of uropathogenic E.coli. A cross sectional & analytical study the conducted in a Tertiary Care centre involving Medical, Surgical, Nephrology, Urology, Paediatrics, Paediatrics Medicine, Paediatrics Surgery & Ob- Gyn, Outpatient departments. A Midstream sample of urine collected and by routine methods the uropathogens were isolated, and UPEC’s virulence factors determined and antibiogram for the same done. The study was undertaken to find out UPEC strains and virulence factors like Haemolysin, Haemagglunation, Cell surface hydrophobicity, Serum resistance shown by Serum Bactericidal assay and Serotyping were detected. Among 320 urinary samples 138 UPEC identified by the above said virulence factors. Antibiogram done by Disc diffusion method in Muller Hinton agar by following NCCLS guidelines. This study showed incidence of UTI more in female, especially in postmenopausal women, Among children UTI more common in males. UPEC is one is the most important cause of UTI and its important virulence factors are haemolysin, haemagglutination, cell surface hydrophobicity and serum resistance were detected.
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