Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2016: 92.3
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3
For more details click here
journals IJCMAS
See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(3): 891-895
DOI: https://doi.org/10.20546/ijcmas.2017.603.104


Microbiological Profile and Antimicrobial Sensitivity Pattern of Endotracheal Tube Aspirates of Patients in ICU of a Tertiary Care Hospital in Bhopal, India
Deepti Chandra*, Avinash Laghawe, K. Sadawarte, Tukaram Prabhu
Department of Microbiology, People’s College of Medical Sciences and Research Centre, Bhopal (M.P), India
*Corresponding author
Abstract:

Mechanical ventilation is a life-saving procedure, but it is associated with a high risk of acquiring respiratory infections. Hence to prevent it and initiate empirical antimicrobial therapy, knowledge of microbial profile and their local antimicrobial sensitivity pattern are essential. A prospective analytical study of Endotracheal tube (ETT) aspirates of mechanically ventilated patients in Intensive Care Unit (ICU) was done over a period of six months (Dec2015-May2016). Endotracheal tube aspirates of patients who had been incubated for ≥48hrs were processed by standard methods with the aim to identify the microbiological profile of ETT aspirates and their antibiogram. Out of the 47 samples, 72.3% were culture positive. Gram negative enteric aerobic bacteria were isolated from most of the patients, most common being Klebsiella species (32.35%), followed by Acinetobacter and Pseudomonas. Most of the Gram negative isolates were sensitive to Meropenem, Tigecycline, and Polymixin B but resistant to Penicillin derivatives and Cephalosporins. Gram positive cocci were mostly sensitive to Penicillin derivatives, Vancomycin and Clindamycin. Gram negative organisms are predominant isolates of ETT in our ICU. Hence empirical therapy, based on bacteriological profile and susceptibilities is essential to prevent poor outcomes in incubated patients.


Keywords: Endotracheal tube ETT,Klebsiella, Acinetobacter.
Download this article as Download

How to cite this article:

Deepti Chandra, Avinash Laghawe, K. Sadawarte, Tukaram Prabhu. 2017. Microbiological Profile and Antimicrobial Sensitivity Pattern of Endotracheal Tube Aspirates of Patients in ICU of a Tertiary Care Hospital in Bhopal.Int.J.Curr.Microbiol.App.Sci. 6(3): 891-895. doi: https://doi.org/10.20546/ijcmas.2017.603.104