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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(4): 266-272
DOI: https://doi.org/10.20546/ijcmas.2020.904.032


Prevalence of Non-responders among Medical Laboratory Technicians and Staff Nurses Evaluated for Anti Hepatitis B Surface Antigen Titre
Balamurali, R. Sujith*, K. V. Leela, A. Karthik and T. Jayaprakash
Department of Microbiology, SRM Medical College Hospital and Research Centre,
SRM Institute of Science and Technology, Kattankulathur – 603203,
Kancheepuram District, Tamilnadu, India
*Corresponding author
Abstract:

Hepatitis B Infection is an occupational high risk factor. Immune response for vaccination was measured by Antibody to Hepatitis B surface antigen (anti HBs) levels. A course of Hep B vaccine yields a protective immune response (anti-HBs ≥10 mIU/mL) this study was designed to determine the anti HBs levels in Health Care Workers (HCWs) working as laboratory technician and staff nurses. The blood samples were collected from 546 HCWs, Anti HBs level was estimated using Chemi Luminescence Immuno Assay (CLIA) before and after 0,1,6 month of vaccination. Among 546 HCWs, before vaccination 83HCWs was non-protected, after 0th dose of vaccination among 83 HCWs, 25 were again not protected. After administer two more doses, 4 were again non-protected. These 4 HCWs was termed as “Non Responders”, have confirmed there vaccination history of complete dose with evidence and has remained to be non-protective after the two sets of complete vaccination course administered.


Keywords: Antibody to Hepatitis B surface antigen, Hepatitis B virus, Chemi Luminescence Immuno Assay, Health care workers, Non responders, Hepatitis B Infection
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How to cite this article:

Balamurali, V., R. Sujith, K. V. Leela, A. Karthik and Jayaprakash, T. 2020. Prevalence of Non-responders among Medical Laboratory Technicians and Staff Nurses Evaluated for Anti Hepatitis B Surface Antigen Titre.Int.J.Curr.Microbiol.App.Sci. 9(4): 266-272. doi: https://doi.org/10.20546/ijcmas.2020.904.032