National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
LRTIs are one of the most common infectious diseases of humans. They are associated with morbidity and mortality worldwide. This study aims to find out the bacterial profile of lower respiratory tract infections in adults and the antibiotic susceptibility pattern of the isolated pathogen including detection of MRSA, ESBLs and MBLs. This study was conducted for a period of 6 months from March to August 2015 at a tertiary care hospital, Chennai. A total of 830 samples were collected during the study. They were processed following standard laboratory protocol. Antibiogram was done using appropriate antibiotics by Kirby-Bauer disc diffusion method and the occurrence of MRSA, ESBLs and MBLs was seen. Out of the 830 samples, 480 (57.8%) were male and 350 (42.2%) were female. 426 (51%) samples showed growth of pathogenic bacteria. Patients in the age group 41-50 were predominantly affected. Klebsiella pneumoniae (57.5%) was found to be the commonest organism isolated followed by Pseudomonas aeruginosa (28.8%). 90% of Klebsiella pneumoniae, 95.6% of Pseudomonas aeruginosa were sensitive to Piperacillin-tazobactum. ESBL was detected to be 33%, MBL was detected to be 3.2%, MRSA was detected to be 25%.All the MRSA isolates were sensitive to vancomycin. All the ESBL isolates were sensitive to Imipenem. Klebsiella pneumoniae and Pseudomonas aeruginosa were the commonest bacteria causing lower respiratory tract infection in adults in this centre. Multidrug resistance among the isolates was common. Periodic analysis of Sputum culture and their antibiotic sensitivity report should be made to identify the changing trends in etiological and sensitivity patterns.
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