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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(3): 2715-2721
DOI: https://doi.org/10.20546/ijcmas.2020.903.310


Evaluation of Microfilaricidal Efficacy of Doxycycline, Ivermectin and Selamectin in Dogs Naturally Infected with Dirofilaria repens
D. S. Malatesh*, C. Ansar Kamran, K. J. Ananda, K. Ganesh Udupa, Ramesh, P.T. Suguna Rao and N. B. Shridhar
Department of Veterinary Medicine, Veterinary College, KVAFSU, Shivamogga-577 204 Karnataka, India
*Corresponding author
Abstract:

The present study was conducted to evaluate the microfilaricidal efficacy of doxycycline, ivermectin and selamectin in dogs naturally infected with D. repens. A total of eighteen dogs positive for microfilaria by modified Knott's method were included in the study. The species of microfilaria was identified as D. repens based on the morphology and micrometry by modified Knott's and Giemsa’s staining technique. The dogs were divided in to doxycycline, ivermectin and selamectin group with six dogs in each group. The drugs were administered as per standard protocol. The blood samples of dogs from all three groups were analysed for microfilarial count before treatment (0 day), 7th and 14th day of post-treatment. The study demonstrated that, the dogs treated with selamectin showed significant reduction in the microfilarial count from 0 day to 14th day with complete elimination of microfilaria in few dogs followed by ivermectin group which also showed significant reduction in the microfilarial count but, without complete removal of microfilaria in any of the dogs in the group. Even though, decrease in the microfilarial count was observed in dogs treated with doxycycline, they were ineffective in reducing the number of microfilaria significantly.


Keywords: Microfilaricidal, D. repens, Efficacy, Doxycycline, Ivermectin, Selamectin, Dogs
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How to cite this article:

Malatesh, D. S., C. Ansar Kamran, K. J. Ananda, K. Ganesh Udupa, Ramesh, P.T. Suguna Rao and Shridhar, N. B. 2020. Evaluation of Microfilaricidal Efficacy of Doxycycline, Ivermectin and Selamectin in Dogs Naturally Infected with Dirofilaria repens.Int.J.Curr.Microbiol.App.Sci. 9(3): 2715-2721. doi: https://doi.org/10.20546/ijcmas.2020.903.310