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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(2): 2895-2905
DOI: https://doi.org/10.20546/ijcmas.2020.902.329


Microbial Profile of Blood Stream Infections and their Antibiotic Susceptibility Pattern of Isolates among Paediatric Patients admitted in a Teaching Hospital of West Bengal
Nishant Kumar, Retina Paul* and Kuhu Pal
Department of Microbiology, College of Medicine & JNM Hospital, WBUHS, Kalyani, West Bengal, India
*Corresponding author
Abstract:

Blood stream infections (BSI) are a global burden in developing countries. Increased incidence leads to morbidity and mortality in neonates as well as Paediatric age group patients. Blood culture is an effective tool for diagnosis of BSI. Aim is to determine various blood stream pathogens and their antibiotic susceptibility pattern. Blood Samples were received during February to August 2018 in JNM hospital of age group up to 12 years and incubated at BacT/ ALERT 3D System. Positives were subcultured on Blood and MacConkey agar and incubated at 37 °C for 18-24 hrs. Standard biochemical test and antibiotic susceptibility test (AST) were performed according to CLSI guidelines. Among 140 Blood samples, 73 (52.1%) were culture positive among the positive samples 36 (49.3%) in neonates, 13 (17.8%) in infants, and 24 (32.9%) in Paediatric patients. 39 (53.4 %) isolates were Gram-positive cocci (GPC) and 25 (35.6 %) were Gram-negative bacilli (GNB) and 8 (11%) were Candida spp. Among GPC, Staphylococcus aureus33 (45.83%) were predominant isolates. Out of which 14 (42.42 %) were Methicillin resistant Staphylococcus aureus (MRSA). While among GNB most frequent isolates were Pseudomonas aeruginosa 9 (12.3%) followed by Acinetobacter spp 6 (8.2%). Multi Drug Resistant (MDR) was observed in GNB. We can conclude from our study that changing trends of microbial isolates and continuous monitoring of antibiotic susceptibility pattern may help clinicians to choose wisely the empirical therapy for responsible pathogen of BSI.


Keywords: Blood stream infections, Methicillin resistant Staphylococcus aureus, Gram-positive cocci, Gram-negative bacilli
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How to cite this article:

Nishant Kumar, Retina Paul and Kuhu Pal. 2020. Microbial Profile of Blood Stream Infections and their Antibiotic Susceptibility Pattern of Isolates among Paediatric Patients admitted in a Teaching Hospital of West Bengal.Int.J.Curr.Microbiol.App.Sci. 9(2): 2895-2905. doi: https://doi.org/10.20546/ijcmas.2020.902.329