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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(1): 190-192
DOI: http://dx.doi.org/10.20546/ijcmas.2016.501.016


Inhibition of Growth, Biofilm and Lecithinase of E. coli by Extract of Neem Leaves (Azadirachta indica)
S. Bhattacharyya, A. Sarfraz, N.K. Jaiswal, A. Sengupta, R.Kumar, D. Kumar, S. Singh and A. Kumar
Department of Microbiology, AIIMS Patna, India
*Corresponding author
Abstract:

Escherichia coli is a Gram negative bacillus belonging to Enterobacteriaceae family, causing a plethora of human infections like Urinary tract infection (UTI), meningitis, diarrhoea and others. It is often resistant to multiple antibiotics. High cost of antibiotics, cost of prolonged hospital stay and refractoriness to drugs necessitates the invention of new, natural and low-cost compounds that can be effective against it. We here report the efficacy of extract of Neem leaves in inhibiting growth, bioflm formation and phospholipase (lecithinase), an important virulence determinant of E. coli. Furthermore, the extract was completely non-toxic to humnan RBCs and WBCs.


Keywords: Escherichia coli, growth, Biofilm, Lecithinase
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How to cite this article:

Int.J.Curr.Microbiol.App.Sci. 5(1): 190-192. doi: http://dx.doi.org/10.20546/ijcmas.2016.501.016