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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(1): 2588-2596
DOI: https://doi.org/10.20546/ijcmas.2020.901.293


Antibiotic Profile of Pseudomonas aeruginosa Isolated from Patients Visiting Grecian Super Specialty Hospital, Mohali, India
Manpreet Kaur1* and Lovleen Pal2
1Department of Microbiology, Grecian Super Specialty Hospital, Sector 69, Mohali, India 2Department of Anaesthesia, Max Hospital, Mohali, India
*Corresponding author
Abstract:

Antimicrobial resistance especially in Pseudomonas spp. is an increasing problem across the world and therefore, its trend of antimicrobial resistance requires to be studied. The objective of current study was to determine the prevalence of Pseudomonas aeruginosa in various clinical samples collected during study and to analyze the antibiotic susceptibility patterns of various drugs against it. During the study, a total of 231 P. aeruginosa isolated from 870 clinical samples like brancho-alveolar fluid (BAL), blood, endotracheal secretion, Foleys tip culture, pleurineral flurineid, pus, spurineturinem, sputum, swab curinelturinere, urine and wound. Antibiotic susceptibility testing were carried out according to the recommendations of Clinical Laboratory Standards Institute (CLSI) guidelines. The highest number of Pseudomonas infections was found in urine, followed by endotracheal, blood, BAL, spurineturinem, wound, pus, foley’s tip, pleurineral flurineid, sputum and swab. Tobracef was the most active drug tested (82.25% susceptible), followed by pipercillin+tazobactam (74.89% susceptible), cefoperazone+sulbactam (67.10% susceptible), meropenem (64.94% susceptible) and ceftazidime (60.17% susceptible). From the present study, it appears that lower respiratory tract infection was the most common hospital acquired infection caused by multidrug resistant (MDR) P. aeruginosa. Moderate rates of drug resistance among P. aeruginosa isolates were observed against ceftazidime and meropenem. This pattern of resistance indicates probable overuse of broad-spectrum antibiotics without the having knowledge of sensitivity patterns of drugs. So there is a continuous need of conduction of surveillance programmes to recommend appropriate therapy to patients. Moreover, our data also demonstrated that Tobracef has enhanced in-vitro antibacterial activity and exhibited 17> % superiority over meropenem. Therefore, it can be a better choice to treat the infections caused by multi-drug resistant P. aeruginosa.


Keywords: Pseudomonas aeruginosa, clinical isolates, Resistant, Susceptible.
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How to cite this article:

Manpreet Kaur and Lovleen Pal. 2020. Antibiotic Profile Of Pseudomonas aeruginosa Isolated From Patients Visiting Grecian Super Specialty Hospital, Mohali, India.Int.J.Curr.Microbiol.App.Sci. 9(1): 2588-2596. doi: https://doi.org/10.20546/ijcmas.2020.901.293