National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Clinical case is five years old female Labrador dog presented to Small Animal Medicine unit of TVCC, VCRI, Orathanadu. History is dullness and anorexia two days. Recurrent tick infestations, anemic and thrombocytopenic crisis were regularly. Vaccination and deworming were regularly. Physical examination revealed dullness, pale mucosa, vital parameters were normal and ticks on interdigital space and in ears were noticed. Distended abdomen, hepatosplenomegaly and petechial hemorrhage on ventral abdomen were observed. Hematology revealed anemia and thrombocytopenia. Negative for blood born parasites in peripheral blood smear. Serum biochemical and urine analysis found to be normal. Serum and EDTA blood were submitted for molecular testing. Flow cytometry revealed Immune-mediated hemolytic anemia (IMHA) and Immune-mediated thrombocytopenia (IMTP). MAT negative for leptospira. Babesia canis positive by PCR method at 394bp. Haematology alteration was studied before and after therapy. Ultrasonography revealed hepatosplenomegaly. Based on PCR and flow cytometry the case was confirmed Evans syndrome with Concurrent Babesia canis in a Labrador dog. Dog treated with Inj. Diminazene aceturate @ 3.5mg/kg IM single dose, Inj. Ringers lactate @ 100 ml IV, Inj. Ascorbic acid @ 5 ml IV, Inj. Vitamin B complex @ 1ml IV, Inj. Prednisone @ 0.5mg/ kg IM, Tab. Doxycycline @ 10mg/kg PO and Syrup. Thrombup @ 15 ml BID PO. Dog showed clinical improvement as well as hematology parameters.
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