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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(11): 1911-1915
DOI: https://doi.org/10.20546/ijcmas.2019.811.224


Studies on Seroconversion of the Live Attenuated Lentogenic Strain of PPMV -1 Vaccine
Raya Sarkar1*, Chanchal Guha2, Ujjwal Biswas3 and Partha Sarathi Jana4
Department of Veterinary Epidemiology and Preventive Medicine, West Bengal University of Animal and Fishery Sciences, 37 & 68 Kshudiram Bose Sarani, Kolkata – 700 037,West Bengal, India
*Corresponding author
Abstract:

The present study was carried out to know the seroconversion of the live attenuated lentogenic strain of PPMV -1 vaccine in field level. Seroconversion study was undertaken to assess the antibody status of the pigeons which are vaccinated with pigeon paramyxovirus type 1(PPMV- 1) vaccine (local isolate) in different areas of the districts Nadia, 24 Parganas (North), and Kolkata in West Bengal, India during the period from June 2016 to May 2017. One thousand pigeons were selected from the different villages/ areas of the Nadia district, 24 Parganas (North) and Kolkata for the study. All the pigeons were vaccinated with live attenuated lentogenic strain PPMV-1 vaccine (local isolate)@ 106.5 EID50 per dose to each bird intranasally ignoring the age of the birds and booster dose was given after 21 days of 1st vaccination and further, revaccination was done every 2 months interval. Serum samples were separated ascetically and individually. Antibody titres were assessed from individual serum sample by haemagglutination inhibition (HI). The mean antibody titre before first vaccination was very negligible (0.1195 ± 0.0379) which was below protective level (25 or 1.50 ± 0.00). After first vaccination the mean antibody titre increased significantly (P ≤ 0.01) and reached to 1.4822 ± 0.0278 which was also considered below protective level before boostering i.e. 21 days of post first vaccination. Again the means antibody titre increased significantly (P ≤0.01) after boostering and persisted above protective level i.e. reached to 1.9599± 0.0351 on 2 (tow) months of post boostering (i.e. 81st days study). That higher level of titres always persisted significantly (0 ≤ 0.01) above protective level up to 8 (eight) months of post boostering, (i.e. 261st days study). Thus, after first vaccination the mean antibody titre increased significantly and reached just below protective level. After boostering and regular revaccination every 2 months interval the antibody titre always persisted above protective level throughout the study period.


Keywords: PPMV -1 vaccine, Live attenuated lentogenic strain, Pigeons
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How to cite this article:

Raya Sarkar, Chanchal Guha, Ujjwal Biswas and ParthaSarathi Jana. 2019. Studies on Seroconversion of the Live Attenuated Lentogenic Strain of PPMV -1 Vaccine.Int.J.Curr.Microbiol.App.Sci. 8(11): 1911-1915. doi: https://doi.org/10.20546/ijcmas.2019.811.224