National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was carried out to know the seroconversion of the live attenuated lentogenic strain of PPMV -1 vaccine in field level. Seroconversion study was undertaken to assess the antibody status of the pigeons which are vaccinated with pigeon paramyxovirus type 1(PPMV- 1) vaccine (local isolate) in different areas of the districts Nadia, 24 Parganas (North), and Kolkata in West Bengal, India during the period from June 2016 to May 2017. One thousand pigeons were selected from the different villages/ areas of the Nadia district, 24 Parganas (North) and Kolkata for the study. All the pigeons were vaccinated with live attenuated lentogenic strain PPMV-1 vaccine (local isolate)@ 106.5 EID50 per dose to each bird intranasally ignoring the age of the birds and booster dose was given after 21 days of 1st vaccination and further, revaccination was done every 2 months interval. Serum samples were separated ascetically and individually. Antibody titres were assessed from individual serum sample by haemagglutination inhibition (HI). The mean antibody titre before first vaccination was very negligible (0.1195 ± 0.0379) which was below protective level (25 or 1.50 ± 0.00). After first vaccination the mean antibody titre increased significantly (P ≤ 0.01) and reached to 1.4822 ± 0.0278 which was also considered below protective level before boostering i.e. 21 days of post first vaccination. Again the means antibody titre increased significantly (P ≤0.01) after boostering and persisted above protective level i.e. reached to 1.9599± 0.0351 on 2 (tow) months of post boostering (i.e. 81st days study). That higher level of titres always persisted significantly (0 ≤ 0.01) above protective level up to 8 (eight) months of post boostering, (i.e. 261st days study). Thus, after first vaccination the mean antibody titre increased significantly and reached just below protective level. After boostering and regular revaccination every 2 months interval the antibody titre always persisted above protective level throughout the study period.
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