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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(11): 1825-1831
DOI: https://doi.org/10.20546/ijcmas.2019.811.214


Study of Prevalence of Pseudomonas aeruginosa in Various Clinical Samples and Investigation of its Antibiotic Sensitivity Pattern
Pratik M. Bezalwar1* and Vijay N. Charde2
1Department of Microbiology, Chintamani College of Arts and Science, Gondpipri, Dist- Chandrapur (MS)-442702, India
2Department of Microbiology, Taywade College, Mahadula-Koradi, Dist- Nagpur, (MS) - 441 111, India
*Corresponding author
Abstract:

Management of Pseudomonas aeruginosa becomes a challenge because of its ability of development of resistance by intrinsic and acquired mechanisms. This resistance mechanism makes the treatment of such pathogen difficult, thus multidrug resistance is acquiring in many strains. The present study aimed to generate the sufficient data regarding the prevalence and antibiotic sensitivity data. Various clinical samples of Blood, Pus, Sputum and Urine were collected and then subjected to their identification by Cultural, Biochemical, Morphological identification and then identified by Vitek 2 system. Then, the identified isolates were screened for the antibiotic sensitivity pattern by disc diffusion method. The results were interpreted according to CLSI 2007 guidelines. Out of 300 isolates tested significant resistant to antibiotics, CAZ (73 isolates) then CPZ (56 isolates), DOR (54 isolates), LE & GEN (53 isolates), PB (52 isolates), CTX (46 isolates), MZ (39 isolates), CTR (16 isolates) and CB (15 isolates) were detected. The results obtained in the study shows many antibiotics are losing efficacy. Thus, the result says that it proper legislation, practice and awareness among the community is needed use antibiotic as therapeutic agent in future generation.


Keywords: Pseudomonas aeruginosa, Multidrug resistance, Therapeutic agent, Antibiotic sensitivity
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How to cite this article:

Pratik M. Bezalwar and Vijay N. Charde. 2019. Study of Prevalence of Pseudomonas aeruginosa in Various Clinical Samples and Investigation of its Antibiotic Sensitivity Pattern.Int.J.Curr.Microbiol.App.Sci. 8(11): 1825-1831. doi: https://doi.org/10.20546/ijcmas.2019.811.214