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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(2): 1069-1079
DOI: http://dx.doi.org/10.20546/ijcmas.2017.602.120


A Study on Malignant Melanoma
M. Datta Prasad*, B. Ananda Rama Rao and P. SaiKumar
Department of Surgery, SVS Medical College Mahabubnagar TS 5009002, India
*Corresponding author
Abstract:

Malignant melanoma is malignancy arising from the melanocytes of skin and mucous membrane. Malignant melanoma is most common skin cancer accounting for 78% of skin cancer related deaths. Cho et al., (2005) reported that the risk factors for the melanoma are higher age, male sex, family history of melanoma, higher number of nevi, severe sun burn, light hair color, the data obtained from three large cohort studies. Histopathological classification comprises of 4 subtypes, these are 1. Superficial spreading type, 2. Nodular melanoma, 3. Lentigomaligna melanoma, 4. Acral lentigenous melanoma. Clinical presentation of melanoma depends on location of tumor. Mostly it present as irregular pigmented lesion that grown or changed over time. In our clinical experience we came across different type of melanoma by its site and presentation, which includes melanoma rectum, melanoma sole, melanoma nail bed, melanoma scalp, melanoma foot, melanoma in interdigital area of toes. Melanoma rectum though rare is also entity. Treatment of melanoma varies depending on many factors such as site of presentation, Clark level, and Breslow thickness, having metastasis, and stage of the tumor. Melanoma treatment consists of wide local excision, systemic therapy with ipilimumab, and radiotherapy, intralesional injection of Talimogene, BCG and INF. The clinician should have sound knowledge of various presentations and staging of malignant melanoma and different treatment modalities for each staging. Here we share our experience with malignant.


Keywords: Melanoma,Clark levels, Breslow thickness
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How to cite this article:

Datta Prasad, M., B. Ananda Rama Rao and SaiKumar, P. 2017. Malignant Melanoma.Int.J.Curr.Microbiol.App.Sci. 6(2): 1069-1079. doi: http://dx.doi.org/10.20546/ijcmas.2017.602.120