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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(11): 67-79
DOI: https://doi.org/10.20546/ijcmas.2019.811.008


A Prospective Comparative Study of Peripheral Blood Smear, Modified Centrifuged Buffy Coat Smear and Rapid Malaria Antigen Detection Test in Diagnosing Malaria at a Tertiary Care Hospital in Western Maharashtra, India
Sonal Thavare1, Chaya A. Kumar1*, Sujata Baveja1, Mohit Wadhi2 and Jai Juvekar2
1LTMMC & Sion Hospital, Mumbai, Maharashtra, India 2Speciality Medical Officer, NMMC, Vashi, Mumbai, Maharashtra, India
*Corresponding author
Abstract:

Malaria is a life-threatening parasitic disease and is a major public health problem. Considering the prevalence of malaria infection in India, there is an urgent need to look for tests that are simple, inexpensive and can be used to improve diagnosis, so that accurate treatment and management can be done. Present study was undertaken to compare and study the efficacy of peripheral blood smear (PBS), modified centrifuged buffy coat smear (CBCS) and rapid malaria antigen detection test (RDT) in malarial diagnosis. The study included all cases with fever for >24 hours. Patients who came for follow up visit of an earlier episode of malaria or within 4 weeks of post treatment were excluded. For statistical analysis of results, RDT was used as gold standard. Highest number of cases were detected by RDTs (97.83%) followed by CBCS (91.30%). PBS was found to be a better test to diagnose malaria than RDT. CBCS were found to be of less utility in diagnosing malaria as compared to RDT. CBCS would be especially useful with negative or low parasitic index (PI) which may be missed by the conventional PBS. Hence, present study concludes that, the CBCS method can be adopted in the routine as it just needs an additional centrifugation procedure to the conventional method making PBS. Key words Malaria, Peripheral blood smear, centrifuged buffy coat smear, Rapid malaria antigen detection test


Keywords: Malaria, Peripheral blood smear, Centrifuged buffy coat smear, Rapid malaria antigen detection test
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How to cite this article:

Sonal Thavare, Chaya A. Kumar, Sujata Baveja, Mohit Wadhi and Jai Juvekar. 2019. A Prospective Comparative Study of Peripheral Blood Smear, Modified Centrifuged Buffy Coat Smear and Rapid Malaria Antigen Detection Test in Diagnosing Malaria at a Tertiary Care Hospital in Western Maharashtra, India.Int.J.Curr.Microbiol.App.Sci. 8(11): 67-79. doi: https://doi.org/10.20546/ijcmas.2019.811.008