National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Everyone tries to relieve stress by taking anti-stress drugs. However, synthetic anti-stress drugs have unwanted side effects, expensive and not readily accessible. Thus, we aimed at investigating the anti-stress activities of aqueous extract of Musanga cecropioides stem bark using forced swimming endurance stress test, anoxia stress tolerance, chronic cold resistance stress test and DPPH radical scavenging capacity. Daily administration of aqueous extract of M. cecropioides at doses of 100, 200 and 300mg/kg bodyweight one hour prior to induction of stress, at the lowest dosage (100 mg/kg)significantly increased the anoxia stress and forced swimming endurance stress tolerance times in a dose dependent manner as compared to the control groups (46.48±0.28 and 3.01±0.92 compared 28.80±0.38 and 2.25±0.08 mins), the blood glucose, blood cells, and the urinary ascorbic acid were normalised in all the tested methods including chronic cold stress. The extract also scavenged DPPH significantly in a dose dependent manner. The results showed impressive anti-stress potential and present as far as is known, the first report of the anti-stress (adaptogenic) activities of M. cecropioides.
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