National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Enteric fever is an endemic disease in India and Widal test is widely used for its diagnosis and to plan treatment. Interpretation of Widal test depends upon the antibody titer present amongst the healthy, asymptomatic individuals in that geographical area. Aim: To determine the Endemic titer of Salmonella enterica subspecies enterica serovar Typhi and Paratyphi among healthy individuals in Meerut City and to find out the local recommendations for the interpretation of Widal test. Materials and methods: A total of 600 serum samples collected from healthy individuals were subjected for Widal tube agglutination test with commercially available antigens of Salmonella enterica subspecies enterica serovar Typhi O and H antigens, serovar paratyphi AH antigen and paratyphi BH antigen . Interpretation of the test was done using standard guidelines. Result: Majority of the samples tested 79.33%, 92%, 94.33% and 100 % had a titer of ≤ 1:20 for anti-O agglutinins, anti-H agglutinins, anti -AH agglutinins and anti- BH agglutinins respectively. The baseline endemic titer was up to 1:80 for S. typhi O and H, upto 1:40 for S. paratyphi AH is and upto 1:20 for BH. Conclusion: Periodic evaluation of baseline antibody titer in a healthy population is important because the titer may change over the years. Knowledge of the baseline antibody titer in that geographical area will help in proper interpretation of the test result which will ultimately decide the treatment outcome of the patient and limit antimicrobial resistance
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