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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(10): 2264-2269
DOI: https://doi.org/10.20546/ijcmas.2019.810.262


Baseline Antibody Titer against Salmonella enterica Subspecies enterica serovar Typhi and Paratyphi among Healthy Individuals from Meerut City: A Periodic Evaluation
Abhigyan Goel, Navdeep Gambhir, Arjun K. Bisht and Anita Pandey*
Department of Microbiology, Subharti Medical College, Meerut, Uttar Pradesh 250001, India
*Corresponding author
Abstract:

Enteric fever is an endemic disease in India and Widal test is widely used for its diagnosis and to plan treatment. Interpretation of Widal test depends upon the antibody titer present amongst the healthy, asymptomatic individuals in that geographical area. Aim: To determine the Endemic titer of Salmonella enterica subspecies enterica serovar Typhi and Paratyphi among healthy individuals in Meerut City and to find out the local recommendations for the interpretation of Widal test. Materials and methods: A total of 600 serum samples collected from healthy individuals were subjected for Widal tube agglutination test with commercially available antigens of Salmonella enterica subspecies enterica serovar Typhi O and H antigens, serovar paratyphi AH antigen and paratyphi BH antigen . Interpretation of the test was done using standard guidelines. Result: Majority of the samples tested 79.33%, 92%, 94.33% and 100 % had a titer of ≤ 1:20 for anti-O agglutinins, anti-H agglutinins, anti -AH agglutinins and anti- BH agglutinins respectively. The baseline endemic titer was up to 1:80 for S. typhi O and H, upto 1:40 for S. paratyphi AH is and upto 1:20 for BH. Conclusion: Periodic evaluation of baseline antibody titer in a healthy population is important because the titer may change over the years. Knowledge of the baseline antibody titer in that geographical area will help in proper interpretation of the test result which will ultimately decide the treatment outcome of the patient and limit antimicrobial resistance


Keywords: Enteric fever, Widal, Baseline titer, Salmonella, Endemic
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How to cite this article:

Abhigyan Goel, Navdeep Gambhir, Arjun K. Bisht and Anita Pandey. 2019. Baseline Antibody Titer against Salmonella enterica Subspecies enterica serovar Typhi and Paratyphi among Healthy Individuals from Meerut City: A Periodic Evaluation.Int.J.Curr.Microbiol.App.Sci. 8(10): 2264-2269. doi: https://doi.org/10.20546/ijcmas.2019.810.262