National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Healthcare associated pneumonia (HAP) that includes ventilator-associated pneumonia (VAP) is the second most common Hospital acquired infection (HAI) only after urinary tract infection accounting for about 15-20% of HAIs. 39% of HAP is VAP. Mortality rate among patients with VAP ranges from 24-50%. Therefore, this study was undertaken with an aim to determine incidence, bacterial profile and antimicrobial susceptibility pattern of VAP in a tertiary care hospital at Andhra Pradesh, India. The patients were suspected of VAP, when Clinical Pulmonary Infection Score (CPIS) was six or greater. Endotracheal aspirate (ETA) from such patients was sent to culture and sensitivity test. Out of 85 patients, 23 patients developed VAP, based on CIPS and culture and sensitivity test. Incidence rate of VAP was found to be 20 per 1000 ventilator days. 22 out of 23 were bacterial pathogens and one was Candida albicans. Predominant bacteria was Acinetobacter spp (52%) followed by Pseudomonas aerugenosa (26%) and members of family Enterobacteriaceae (17%). Gentamicin was found as most effective antimicrobial agent to all gram negative bacteria obtained. Gram negative bacteria are common pathogens of VAP throughout the world. However, antimicrobial susceptibility testing is necessary for determination of antimicrobial therapy as it shows regional variation.
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