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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(2): 778-787
DOI: http://dx.doi.org/10.20546/ijcmas.2017.602.086


Correlation between Body Mass Index and Gut Microbiota in Adults
Sally M. Saber1, *Hala B. Othman1, Sherin ElMasry1*, Alaa Magdy1 and Howayda F. Zidan2
1Clinical Pathology Department, Faculty of Medicine, Ain Shams University, Egypt
2 Department of Rheumatology and Rehabilitation, Faculty of Medicine, Ain Shams University, Egypt
*Corresponding author
Abstract:

Gut microbiota has been proposed as a new environmental risk factor responsible for obesity. So, the aim of this study was to assess the gut microbiota profile, with special consideration to Lactobacilli, E. coli and S. aureus viable bacterial count (VBC) in (CFU/gm) and their association with body mass index (BMI) and obesity using quantitative stool culture. This study was conducted on 100 individuals; 74 with disturbed BMI who were divided into subgroups, with no other associated co-morbidities and 26 healthy average weight volunteers. Fresh stool samples were collected and cultured directly on MacConkey, xylose lysine deoxycholate, Blood and Man-Rogoza Sharpe agar and quantitatively with serial dilutions (10-2 – 10-9) in sterile normal saline. S. aureus was not isolated in any group, while, Lactobacilli and E. coli were isolated from all groups. Lactobacilli have a significant low VBC in obese and the highest VBC in the normal weight group showing a negative correlation with BMI. While, E. coli had a significantly high VBC in obese and the lowest in the underweight group showing a positive correlation with BMI. In conclusion, low Lactobacilli VBC and high E. coli VBC are significantly related to increased BMI and thus obesity.


Keywords: Obesity, Lactobacillus reuteri, Lactobacillus paracasei, Lactobacillus plantarum, E. coli, Probiotics, Prebiotics and synbiotics.
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How to cite this article:

Sally M. Saber, Hala B. Othman, Sherin ElMasry, Alaa Magdyand, Howayda F. Zidan. 2017. Correlation between Body Mass Index and Gut Microbiota in Adults.Int.J.Curr.Microbiol.App.Sci. 6(2): 778-787. doi: http://dx.doi.org/10.20546/ijcmas.2017.602.086