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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(2): 618-625
DOI: http://dx.doi.org/10.20546/ijcmas.2017.602.070


Characterization and Antimicrobial Susceptibility Pattern of Clinical Isolates of Enterococci in a Tertiary Care Cancer Hospital, Kerala, India
Swapna Raveendranath*, Remya Nair and Sagila Savithri Gangadharan
Division of Microbiology, Regional Cancer Centre, Thiruvananthapuram, 695 011, India
*Corresponding author
Abstract:

Enterococci have emerged as an increasingly important cause of nosocomial infections in patients with cancer. The emergence of vancomycin-resistant enterococci (VRE) is a cause of concern, as once established, it is very difficult to control. A study on the characterization and antimicrobial susceptibility pattern of clinical isolates of enterococci from patients with cancer was carried out in the Division of Microbiology, Regional Cancer Centre, and Thiruvananthapuram for a period of three months. A total 100 enterococcal isolates obtained from various clinical samples were included in the study. E. faecium (73%) was the predominant enterococcal species isolated in the study followed by E. faecalis (24%) and E. durans (3%). 18 strains (18%) of the enterococcal strains were resistant to vancomycin. Resistant strains had an MIC ranging from 32 µg/ml to 512 µg/ml for vancomycin. All strains were susceptible to linezolid and tigecycline. Vancomycin resistance was observed in a significant percentage of enterococcal isolates. Tigecycline or linezolid should be considered in empirical treatment of presumed enterococcal sepsis. Stringent infection prevention and restricted use of vancomycin are important measures to reduce the prevalence of emergence of resistant enterococci.


Keywords: Enterococcal species, Vancomycin resistance,Infection control.
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How to cite this article:

Swapna Raveendranath, Remya Nair and Sagila Savithri Gangadharan. 2017. Characterization and Antimicrobial Susceptibility Pattern of Clinical Isolates of Enterococci in a Tertiary Care Cancer Hospital, Kerala.Int.J.Curr.Microbiol.App.Sci. 6(2): 618-625. doi: http://dx.doi.org/10.20546/ijcmas.2017.602.070