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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(9): 1752-1723
DOI: https://doi.org/10.20546/ijcmas.2019.809.198


Bacteriological Profile and Antibiogram of isolates from Bloodstream Infections in Patients Admitted in ICU from a Tertiary care hospital, Nerul, Navi Mumbai, India
Jyoti P. Sonawane1, Keertana S. Shetty2, N. Kamath2*, NitinBharos3 and Abhay S. Chowdhary4
1Department of Microbiology, Dr.D.Y.Patil Medical College and Hospital, Nerul, Navi Mumbai, India
2Department of Microbiology, GMC, Silvassa, India
*Corresponding author
Abstract:

Bloodstream infections are frequent and life – threatening, can lead to increase in morbidity, mortality and health care cost of patients admitted in intensive care unit (ICU). In addition to this, infections due to emerging multidrug resistant (MDR) microorganisms, the treatment becomes challenging. With the rising problem of drug resistance, the present study was undertaken to evaluate the most prevalent bacterial pathogen causing Bloodstream infections in adult patients admitted to an Intensive Care Unit (ICU) with their antimicrobial sensitivity pattern. A retrospective analysis of data was done on the blood cultures received from 817 patients with clinically suspected bloodstream infections, admitted in Medical ICU of tertiary care hospital, Navi Mumbai, between October 2016 and October 2018. All the samples were received and processed in the Department of Microbiology, using standard microbiological techniques and antimicrobial sensitivity was done according to CLSI guidelines. From 817 patients, the positive growth for pathogen was observed in 165 (20.19%) patients. 167 isolates were identified, maximum isolates were Gram – negative 120 (71.86%), Gram – positive were 31 (18.56%) and Candida spp. were 16 (9.58%). Among bacterial isolates, there was a predominance of Klebsiella pneumoniae 37 (22.15%) followed by Acinetobacter spp. 31 (18.56%), Escherichia coli 29 (17.36%), Pseudomonas aeruginosa 16 (9.58%) &Enterococcus spp. 14 (8.38%). Gram – negative bacterial pathogens showed decreasing sensitivity to Imipenem, Piperacillin – tazobactum, Aminoglycosides, Third – generation Cephalosporins& Cephalosporin. Whereas all gram – positive bacterial isolates were sensitive to Vancomycin and Linezolid while resistant to Penicillin. This study showed the high prevalence of multi drug resistant gram – negative pathogens causing bloodstream infections in our ICU setting. Thus a continues surveillance of prevalent etiological pathogens of BSI along with their antibiotic susceptibility pattern will be helpful to the clinicians in choosing the proper antimicrobials. And clinical management of BSI will minimize the emergence of multi drug resistance.


Keywords: Bloodstream infections (BSI), Intensive care unit (ICU), Multi drug resistant (MDR), Blood cultures, and Antimicrobial sensitivity.
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How to cite this article:

Jyoti P. Sonawane, Keertana S. Shetty, N. Kamath, NitinBharos and Abhay S. Chowdhary 2019. Bacteriological Profile and Antibiogram of isolates From Bloodstream Infections in Patients Admitted in ICU from a Tertiary care hospital, Nerul, Navi Mumbai, India.Int.J.Curr.Microbiol.App.Sci. 8(9): 1752-1723. doi: https://doi.org/10.20546/ijcmas.2019.809.198