Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(9): 638-642
DOI: https://doi.org/10.20546/ijcmas.2019.809.076


Characterization of Isolated Candida Spp in Blood Stream Infection and its Antifungal Susceptibility Pattern
Meghagevariya and Ekta Gosaliya*
Department of Microbiology, P.D.U Medical College, Rajkot-360001, Gujarat, India
*Corresponding author
Abstract:

The aim of present study was to isolate, identify various species of Candida responsible for producing clinical Candidacies from blood culture and to determine antifungal susceptibility pattern of Candida species by disc diffusion method. study was conducted at Microbiology department P.D.U Medical college Rajkot from March 2014 to June 2015. Blood samples from suspected cases were inoculated in to Brain Heart Infusion broth were incubated at 370C and subcultured routinely. Whenever growth of white opaque colony on Blood agar was noticed, further processed to identify isolated yeast species by Gram’s stain, germ-tube production, Hichrome and cornmeal agar morphology. Within the study period, among 38 candida strains isolated, Candida parapsilosilosis 17 (44.70%), Candida guilliermondii 9 (23.68%), Candida glabrata 6 (15.70%), Candida tropicalis 4 (10.50%), Candida albicans 2 (5.20%). Antifungal susceptibility rates of candida isolates based on disc diffusion method were as follows: amphotericin B (100%), voriconazole (100%) and fluconazole (97.2%). Candida species possess a number of virulence factors responsible for hematogenous disseminated infections in susceptible hosts with increased morbidity and mortality. Characterization of isolated Candida spp in bloodstream infection and any increase in resistance (if any) over time, must be determined with scientific methods. We think that similar studies will guide the clinician in planning treatment of candida infections especially in patients at risk.


Keywords: Candidemia, Candida, Microbial sensitivity tests, Indoor patients
Download this article as Download

How to cite this article:

Meghagevariya and Ekta Gosaliya. 2019. Characterization of Isolated Candida Spp in Blood Stream Infection and its Antifungal Susceptibility Pattern.Int.J.Curr.Microbiol.App.Sci. 8(9): 638-642. doi: https://doi.org/10.20546/ijcmas.2019.809.076