National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The aim of present study was to isolate, identify various species of Candida responsible for producing clinical Candidacies from blood culture and to determine antifungal susceptibility pattern of Candida species by disc diffusion method. study was conducted at Microbiology department P.D.U Medical college Rajkot from March 2014 to June 2015. Blood samples from suspected cases were inoculated in to Brain Heart Infusion broth were incubated at 370C and subcultured routinely. Whenever growth of white opaque colony on Blood agar was noticed, further processed to identify isolated yeast species by Gram’s stain, germ-tube production, Hichrome and cornmeal agar morphology. Within the study period, among 38 candida strains isolated, Candida parapsilosilosis 17 (44.70%), Candida guilliermondii 9 (23.68%), Candida glabrata 6 (15.70%), Candida tropicalis 4 (10.50%), Candida albicans 2 (5.20%). Antifungal susceptibility rates of candida isolates based on disc diffusion method were as follows: amphotericin B (100%), voriconazole (100%) and fluconazole (97.2%). Candida species possess a number of virulence factors responsible for hematogenous disseminated infections in susceptible hosts with increased morbidity and mortality. Characterization of isolated Candida spp in bloodstream infection and any increase in resistance (if any) over time, must be determined with scientific methods. We think that similar studies will guide the clinician in planning treatment of candida infections especially in patients at risk.
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