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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(9): 194-203
DOI: https://doi.org/10.20546/ijcmas.2019.809.025


Systemic and Local Humoral Immune Response against F-1 and LaSota Strains of New Castle Disease Virus in Chicken
Rajesh Singathia1*, Ravindra Sharma2 and Satishkumar Batra2
1Department of Veterinary Microbiology, College of Veterinary and Animal Sciences, Navania, Vallabhnagar, Udaipur-313601 (Rajasthan), India
2Department of Veterinary Microbiology, College of Veterinary Sciences, C.C.S. Haryana Agricultural University, Hisar, India
*Corresponding author
Abstract:

F-1 and LaSota strains of NDV were propagated in laboratory using 10-day old embryonated hen eggs via allantoic cavity route. One group of thirty chicks were infected with F-1strain and other with LaSota strain with 105 egg infective doses in 100 µl of virus via oral and ocular route. Sequential sera samples and tracheal samples at day 0, 3,7,14, 21 and 28 post infection were collected and titre of antibodies indicative of humoral immune response was determined by indirect ELISA. The findings of present study lead to the conclusion that infection with NDV induces production of humoral immune response in chickens. Humoral antibodies generated in responses to NDV infection in chickens are both of local (IgA, IgG) and serum antibodies (IgG and IgM) type. The F-1 strain of NDV appears to be slightly better immunogenic than that of LaSota strain of NDV.


Keywords: Newcastle disease virus, Chicks, Humoral immunity, F-1, LaSota
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How to cite this article:

Rajesh Singathia, Ravindra Sharma and Satishkumar Batra. 2019. Systemic and Local Humoral Immune Response against F-1 and LaSota Strains of New Castle Disease Virus in Chicken.Int.J.Curr.Microbiol.App.Sci. 8(9): 194-203. doi: https://doi.org/10.20546/ijcmas.2019.809.025