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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(8): 230-235
DOI: https://doi.org/10.20546/ijcmas.2019.808.027


Detection of Aminoglycoside-Acetyl Transferase Enzyme Gene (aac(6')-Ib-cr) among Ciprofloxacin Resistant Isolates from the Sudan
Inass A. Malik*
School of Medicine, Ahfad University for Women, Sudan
*Corresponding author
Abstract:

The aim of this study was to determine the prevalence of aac(6')-Ib-cr gene among seventy-two urinary and wound enterobacterial pathogens that were ciprofloxacin-resistant and ESBL producers from the Sudan. All the seventy-two isolates were screened by PCR for the presence of the aac(6')-Ib-cr gene. The new variant of the aminoglycoside acetyle transferase enzyme (aac(6')-Ib-cr) gene was detected among 52 of the 72 test isolates (72%) including Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae and Salmonella spp. This finding shows that the new variant aminoglycoside-acetyl transferase gene conferring resistance to ciprofloxacin is highly prevalent (72%) among the isolates from Sudan. This is the first study to report on the detection of aminoglycoside-acetyl transferase enzyme gene from the Sudan.


Keywords: Ciprofloxacin, Resistance, Enzyme, Plasmid, Enterobacteriaceae
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How to cite this article:

Inass A. Malik. 2019. Detection of Aminoglycoside-Acetyl Transferase Enzyme Gene (aac(6')-Ib-cr) among Ciprofloxacin Resistant Isolates from the Sudan.Int.J.Curr.Microbiol.App.Sci. 8(8): 230-235. doi: https://doi.org/10.20546/ijcmas.2019.808.027