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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 8, Issue:8, August, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(8): 230-235
DOI: https://doi.org/10.20546/ijcmas.2019.808.027


Detection of Aminoglycoside-Acetyl Transferase Enzyme Gene (aac(6')-Ib-cr) among Ciprofloxacin Resistant Isolates from the Sudan
Inass A. Malik*
School of Medicine, Ahfad University for Women, Sudan
*Corresponding author
Abstract:

The aim of this study was to determine the prevalence of aac(6')-Ib-cr gene among seventy-two urinary and wound enterobacterial pathogens that were ciprofloxacin-resistant and ESBL producers from the Sudan. All the seventy-two isolates were screened by PCR for the presence of the aac(6')-Ib-cr gene. The new variant of the aminoglycoside acetyle transferase enzyme (aac(6')-Ib-cr) gene was detected among 52 of the 72 test isolates (72%) including Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae and Salmonella spp. This finding shows that the new variant aminoglycoside-acetyl transferase gene conferring resistance to ciprofloxacin is highly prevalent (72%) among the isolates from Sudan. This is the first study to report on the detection of aminoglycoside-acetyl transferase enzyme gene from the Sudan.


Keywords: Ciprofloxacin, Resistance, Enzyme, Plasmid, Enterobacteriaceae

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How to cite this article:

Inass A. Malik. 2019. Detection of Aminoglycoside-Acetyl Transferase Enzyme Gene (aac(6')-Ib-cr) among Ciprofloxacin Resistant Isolates from the Sudan.Int.J.Curr.Microbiol.App.Sci. 8(8): 230-235. doi: https://doi.org/10.20546/ijcmas.2019.808.027
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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