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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2656-2660
DOI: https://doi.org/10.20546/ijcmas.2019.807.327


COPD and Intestinal Dysbiosis
R.S. Bayramova*, M.S. Novruzova, H.M. Aliyeva and J.X. Talibova
Azerbaijan Medical University, Department of Medical Microbiology and Immunology, Azerbaijan
*Corresponding author
Abstract:

By WHO forecasts, a further increase in the prevalence and mortality of COPD among people of working age is predicted, due to uncontrolled environmental pollution, a tobacco pandemic, an increase in the level of allergens and a genetic predisposition. In chronization and progression of COPD, there is a violation of cellular and humoral immunity, production of pro-inflammatory cytokines of phagocytic cell activity that contribute to the persistence of the inflammatory process in the lungs. Therefore, the study of the state of intestinal microflora in patients with COPD and the timely correction of impaired microbiocinosis is an important task that needs to be studied. Patients with COPD have a chronic inflammatory process in the bronchopulmonary system, accompanied by inhibition of the functional activity of neutrophils, which complicates the formation of humoral immunity and leads to a persistent course of the disease with frequent exacerbations. The revealed violations of COPD associated with intestinal dysbacteriosis indicate pronounced manifestations of secondary immunodeficiency. The obtained data allow us to recommend bacteriological and immunological examination of patients with COPD to identify immunological deficiencies with concomitant intestinal dysbiosis for the purpose of complex treatment with the use of immunocorrecting and probiotics.


Keywords: Chronic obstructive pulmonary, Secondary immunodeficiency, Inflammatory process, Chronization, Phagitosis activity, Normal intestinal microflora, Dysbiotic changes, Bifidus bacteria and lactobacilli, E.coli
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How to cite this article:

Bayramova, R.S., M.S. Novruzova, H.M. Aliyeva and Talibova, J.X. 2019. COPD and Intestinal Dysbiosis.Int.J.Curr.Microbiol.App.Sci. 8(7): 2656-2660. doi: https://doi.org/10.20546/ijcmas.2019.807.327