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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2198-2206
DOI: https://doi.org/10.20546/ijcmas.2019.807.267


Antimicrobial Resistance Pattern in Escherichia coli Causing Urinary Tract Infection among Inpatients - A Retrospective Study
G. Sasikala, Usha Rani Ramavath* and Qader Ahmed Jalily
Department of Microbiology, Mahavir Institute of Medical Sciences, #2-4-40, Shivareddypet, Vikarabad, Ranga Reddy - 501 101, Telangana, India
*Corresponding author
Abstract:

Urinary tract infections (UTIs) are second most common medical problem of humans after respiratory tract infection. They are often recurrent, difficult to treat, and can cause parenchymal damage to the kidney, leading to renal insufficiency and further complications. The aim is to study increasing rates of antimicrobial resistant Escherichia coli (E. coli) among patients admitted with urinary tract infections. The details of E. coli isolates from urine samples and their antibiotic sensitivity pattern were collected from the laboratory registers and the patient details were collected from the case records. The urine samples were processed using standard methods as per CLSI guidelines and antibiotic susceptibility was done by Kirby-Bauer disk diffusion test. Of the total 117 E. coli isolates, 27 (23.8%) were isolated from in-patients, which were considered for the study. Of these 27 E. coli isolates, 15 (55.55%) were multi drug resistant (MDR). The isolates showed high levels of resistance to ampicillin (81.48%), amoxyclav (70.3%), cefuroxime (74.07%), cefazolin (70.37%), cefotaxime (62.96%), cefoxitin (59.26%), Ciprofloxacin (74.07%), norfloxacin (66.67).The isolates were highly sensitive to piperacillin-tazobactum (96.30%), Meropenam (100%), tobramycin (96.30%), aztreonam (74.07%), amikacin (74.07%), nitrofurantoin (74.07%) and, ceftazidime-clavulinic acid (74.07%), co-trimoxazole (74.07%) and tetracycline (55.56%). Of the 15 cases of UTI are due to MDR E. coli, 14 improved on treatment and 1 was referred to higher centres.


Keywords: Antimicrobial resistance, Escherichia coli, MDR, therapy, UTI
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How to cite this article:

Sasikala, G., Usha Rani Ramavath and Qader Ahmed Jalily. 2019. Antimicrobial Resistance Pattern in Escherichia coli Causing Urinary Tract Infection among Inpatients - A Retrospective Study.Int.J.Curr.Microbiol.App.Sci. 8(7): 2198-2206. doi: https://doi.org/10.20546/ijcmas.2019.807.267