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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(6): 2036-2044
DOI: https://doi.org/10.20546/ijcmas.2019.806.243


Evaluation of CD4 Count and Its’ Correlation with Opportunistic Intestinal Parasitic Infections in HIV Seropositive
Rohit Sinha, V.S. Rathod*, S.R. More and S.K. Kandle
Department of Microbiology, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India
*Corresponding author
Abstract:

Human Immunodeficiency Virus (HIV) infection and its end stage, Acquired Immunodeficiency Syndrome (AIDS), is an extremely serious problem worldwide. HIV seropositive patients with CD4 T cell count < 200 cells/μl have reported an excess risk of diarrhoea. The present study was undertaken in the at Dr. S.C.G.M.C, Nanded between November 2015 and October 2017 to identify Opportunistic Intestinal parasites in HIV positive patients presenting with or without diarrhoea and their association with CD4 T cell count. Newly diagnosed 300 patients with HIV infection confirmed by serology were included and divided into two groups Diarrhoeal and non-diarrhoeal. CD4 T lymphocyte cell count was estimated using Flow-Cytometry. Stool specimens were collected from all the patients and examined macroscopically and microscopically. We found that intestinal parasites in subjects with diarrhoea were significantly higher than without diarrhoea. Cryptosporidium sp. was the most common parasite detected. Intestinal parasites were found to be more common in HIV seropositive patients with CD4 cell count < 200 cells/μl. Thus, routine screening of the stool samples of HIV seropositive patients with diarrhoea should be done for prompt patient care and prevent the emergence of fulminant form of the disease.


Keywords: HIV, Opportunistic Parasitic Infections, CD4 count, Cryptosporidium
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How to cite this article:

Rohit Sinha, V.S. Rathod, S.R. More and Kandle, S.K. 2019. Evaluation of CD4 Count and Its’ Correlation with Opportunistic Intestinal Parasitic Infections in HIV Seropositive.Int.J.Curr.Microbiol.App.Sci. 8(6): 2036-2044. doi: https://doi.org/10.20546/ijcmas.2019.806.243