Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(6): 1732-1738
DOI: https://doi.org/10.20546/ijcmas.2019.806.207


Extended Spectrum β-Lactamases and Metallo β-Lactamases Production in Klebsiella pneumoniae Isolates Causing Pneumonia in Rural Population of Uttar Pradesh, India
Nitisha Malik*, Dakshina Bisht and Sameer Singh Faujdar
Department of Microbiology, Santosh Medical College & Hospital Ghaziabad, India
*Corresponding author
Abstract:

The drug resistance among the gram negative bacteria is present as a serious global problem. ESBLs and MBLs are the important members of beta-lactamases produced mainly by gram negative bacteria and are responsible for mediating resistance to extended-spectrum cephalosporins and carbapenem. These enzymes are commonly detected in the members of the Enterobacteriaceae like Klebsiella pneumoniae and Escherichia coli. A cross-sectional study was conducted at Department of Microbiology, Santosh Medical College & Hospital Ghaziabad by using K. pneumoniae isolated from sputum samples. Antimicrobial susceptibility testing was performed by Kirby-Bauer disc diffusion technique. ESBL and MBL production were detected by using phenotypic methods. Out of the 200 sputum samples, 72 samples were confirmed and identified as K. pneumoniae. Out of total 72 isolates, 48 (66.6%) were found to be resistant to Ceftazidime, Ceftriaxone, Cefotaxime and 24 (33%) isolates were found to be ESBL producers. On the other hand 40 (55.5%) isolates were found to be resistant to imipenem and 16 (22.2%) isolates were found to be MBL producers.


Keywords: Klebsiella pneumoniae, Extended Spectrum Βeta-Lactamases (ESBL), Metallo Β-Lactamases (MBL)
Download this article as Download

How to cite this article:

Nitisha Malik, Dakshina Bisht and Sameer Singh Faujdar. 2019. Extended Spectrum β-Lactamases and Metallo β-Lactamases Production in Klebsiella pneumoniae Isolates Causing Pneumonia in Rural Population of Uttar Pradesh.Int.J.Curr.Microbiol.App.Sci. 8(6): 1732-1738. doi: https://doi.org/10.20546/ijcmas.2019.806.207