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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(6): 1115-1122
DOI: https://doi.org/10.20546/ijcmas.2019.806.138


Evolution of Genexpert MTB/RIF Assay for Rapid Diagnosis of Tuberculosis in Extra Pulmonary Sample of Suspected Case of Tuberculosis in Tertiary Care Hospital, Jamnagar, Gujarat (India)
Saurabh Chhotalal Gamit*, Hitesh Kantilal Shingala and Summaiya Mullan
Department of Microbiology, M.P. Shah Govt. Medical College, Jamnagar, India
*Corresponding author
Abstract:

Tuberculosis is caused by various strains of Mycobacteria usually Mycobacterium tuberculosis [1]. It is spread through the air when people who have an active TB infection cough, sneeze, or otherwise transmit respiratory fluids through the air [2]. In 15-20% of active cases, the infection spreads outside the lungs, causing other kinds of TB [4]. These are collectively denoted as “Extra pulmonary Tuberculosis” extra pulmonary TB occurs more commonly in immune suppressed persons and young children. This study was conducted in tertiary care hospital, Jamnagar. Total 230 Extra Pulmonary (Pus, Body Fluid, Abscess, CSF, Lymph nodes, Biopsy, Urine, BAL, Tissue) Suspected case of MTB samples were received during the study period. Out of total 230 Extra pulmonary samples, in 64(27.82%) samples Mycobacterium Tuberculosis Bacilli (MTB) were detected by GeneXpert MTB/RIF Assay. Out of 64 positive extra pulmonary MTB cases, 32(50%) were belongs to male gender and 32(50%) were belongs to female gender, highest numbers of MTB positive cases were found in age group of 11-20 years which were 18(28.1%) followed by 21-30 years which were 15(23.4%). The study revealed the GeneXpert MTB/RIF Assay test offers a potential solution for improving early MTB diagnosis.


Keywords: Mycobacterium tuberculosis, GeneXpert MTB/RIF Assay, Extra pulmonary
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How to cite this article:

Saurabh Chhotalal Gamit, Hitesh Kantilal Shingala and Summaiya Mullan. 2019. Evolution of Genexpert MTB/RIF Assay for Rapid Diagnosis of Tuberculosis in Extra Pulmonary Sample of Suspected Case of Tuberculosis in Tertiary Care Hospital, Jamnagar, Gujarat (India).Int.J.Curr.Microbiol.App.Sci. 8(6): 1115-1122. doi: https://doi.org/10.20546/ijcmas.2019.806.138