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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(1): 433-446
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.052


In vitro Antimicrobial Activity of Some Commercial Toothpastes
Gerald Ngo Teke1*, Ngolle Godwill Enongene2 and Akah Roland Tiagha2
1Department of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda-Cameroon, P.O.Box 39, Bambili
2Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Bamenda-Cameroon, P.O. Box 39, Bambili
*Corresponding author
Abstract:

Despite great improvements in global oral health status, dental caries still remain one of the most prevalent diseases. Yet some brands of toothpastes claim to be effective antimicrobial agents. This study was therefore designed to evaluate the in vitro antimicrobial activity of commercially available toothpastes against some microorganisms involved in tooth infections. Agar disc diffusion method was used to test the antimicrobial activity of ten different toothpastes at various concentrations (1:2; 1:4 and 1:8 dilutions) against Porphyromonas gingivalis, Escherichia coli, Staphylococcus aureus and Candida albicans.  The sensitivity of tested toothpastes towards each microorganism was expressed as a percentage of the mean clear zone diameter. Statistical analysis was performed with the help of Statistical Package for Social Sciences (SPSS) version 19 with significance considered at pP. gingivalis at various levels: Signal (67.3%), Colgate Protection Max (63.6%) and Colgate Herbal (62.7%). Test concentration of 1:2 dilution of these toothpastes was most effective on E. coli with clear zones ranging from 11.7 mm (Oral B) to 23.3 mm (Aloe vera). Generally the inhibition of S. aureus growth by these dentifrices even at higher test concentrations was weak, with clear zones ranging from 8.3 to 15.0 mm. No growth inhibitory activity was observed for Mericle (least effective in bacterial growth inhibition) against C. albicans at all the tested concentrations. Dentix (25.8%), Airsun (30.7%), Special 2 plus (22.2%) and Oral B (22.7%) were equally less sensitive to this microorganism compared to the controls. Our in vitro study has shown antimicrobial activities of the mentioned toothpastes against P. gingivalis, E. coli, S. aureus and C. albicans. Thus they can be used to control dental infections.


Keywords: Oral pathogens, antimicrobial activity, inhibition zone, toothpastes, ingredients.
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How to cite this article:

Gerald Ngo Teke, Ngolle Godwill Enongene and Akah Roland Tiagha. 2017. In vitro Antimicrobial Activity of Some Commercial Toothpastes.Int.J.Curr.Microbiol.App.Sci. 6(1): 433-446. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.052