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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(1): 362-366
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.043


Role of Rapid Test and ELISA in the Diagnosis of HCV in Haemodialysis Patients
Kanaga Priya Muthiah1* and T. Susitha2
1Department of Microbiology, Tirunelveli Medical College, Tirunelveli, India
2Department of Microbiology, KanyaKumari Government Medical College, Asaripallam, India
*Corresponding author
Abstract:

The usefulness of Rapid test and ELISA in the diagnosis of HCV in haemodialysis patients was analysed. In this study, Immuno Chromatography Test [ICT] rapid test was compared with ELISA for the effective detection of anti-HCV antibodies in patients on haemodialysis. A total of 106 blood samples, from chronic renal disease patients on haemodialysis were taken from the Department of Nephrology, Government Medical College Hospital, for a period of six months from July to December 2011. Sera were tested for anti HCV antibodies by rapid ICT and further tested by third generation ELISA. Anti-HCV antibodies were positive in 6 (5.66%) patients by ICT method while 7 (6.6%) patients were positive by ELISA method. The sensitivity and specificity of the ICT kit were 85.7% and 100% respectively whereas positive and negative predictive values were 100% and 99% respectively, which were significantly high and quite equivalent to the ELISA results. An ideal rapid test is a boon in time-saving situations like dialysis. Hence we conclude that HCV screening can be preferably done by a rapid test followed by a supplemental ELISA and polymerase chain reaction.


Keywords: HCV, ICT,ELISA, Haemodialysis, Chronic Kidney disease.
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How to cite this article:

Kanaga Priya Muthiah and Susitha, T. 2017. Role of Rapid Test and ELISA in the Diagnosis of HCV in Haemodialysis Patients.Int.J.Curr.Microbiol.App.Sci. 6(1): 362-366. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.043