National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In the present research work, an in vitro anti-inflammatory activity of twenty-five different medicinal plants growing around Junagadh region of Gujarat was evaluated. Phytochemical screening of each plant extracts was performed. Anti-inflammatory activity was evaluated using two different methods: 1. Inhibition of albumin denaturation and 2. Protease inhibition assay. In case of inhibition of albumin denaturation assay, water extracts of Adansonia digitata L. leaves, Flueggea leucopyrus Willd. leaves and Solanum xanthocarpum Schrad. & H. Wendl. aerial part showed an inhibition of 87.54, 80.23 and 80.38 %, respectively. While methanol extracts of Adansonia digitata L. leaves and Solanum xanthocarpum aerial part exhibited 87.54 and 81.79 % inhibition at 500 µg/ml concentration. In the case of protease inhibition assay, methanol and water extracts of Adansonia digitata leaves, Flueggea leucopyrus leaves and Punica granatum L. epicarp showed the higher inhibition at 500 µg/mL. The methanol extract of Flueggea leucopyrus leaves and water extract of Peltophorum pterocarpum (DC.) K. Heynebark exhibited protease inhibition of 91.94 % and 89.06 %, respectively at higher concentration. The observations from the present study may be useful for bioprospecting in the field of ethnopharmacology.
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