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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(5): 1686-1698
DOI: https://doi.org/10.20546/ijcmas.2019.805.195


Comparative Evaluation of in vitro Anti-Inflammatory Activity of Different Extracts of Selected Medicinal Plants from Saurashtra Region, Gujarat
Chirag M. Modi, Punit R. Bhatt, Kajal B. Pandya, Harshad B. Patel and Urvesh D. Patel
Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science and Animal Husbandry, Junagadh Agricultural University, Junagadh (Gujarat) India
*Corresponding author
Abstract:

In the present research work, an in vitro anti-inflammatory activity of twenty-five different medicinal plants growing around Junagadh region of Gujarat was evaluated. Phytochemical screening of each plant extracts was performed. Anti-inflammatory activity was evaluated using two different methods: 1. Inhibition of albumin denaturation and 2. Protease inhibition assay. In case of inhibition of albumin denaturation assay, water extracts of Adansonia digitata L. leaves, Flueggea leucopyrus Willd. leaves and Solanum xanthocarpum Schrad. & H. Wendl. aerial part showed an inhibition of 87.54, 80.23 and 80.38 %, respectively. While methanol extracts of Adansonia digitata L. leaves and Solanum xanthocarpum aerial part exhibited 87.54 and 81.79 % inhibition at 500 µg/ml concentration. In the case of protease inhibition assay, methanol and water extracts of Adansonia digitata leaves, Flueggea leucopyrus leaves and Punica granatum L. epicarp showed the higher inhibition at 500 µg/mL. The methanol extract of Flueggea leucopyrus leaves and water extract of Peltophorum pterocarpum (DC.) K. Heynebark exhibited protease inhibition of 91.94 % and 89.06 %, respectively at higher concentration. The observations from the present study may be useful for bioprospecting in the field of ethnopharmacology.


Keywords: Medicinal plants, Saurashtra region, Adansonia digitata, Methanol and water extracts
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How to cite this article:

Chirag M. Modi, Punit R. Bhatt, Kajal B. Pandya, Harshad B. Patel and Urvesh D. Patel. 2019. Comparative Evaluation of in vitro Anti-Inflammatory Activity of Different Extracts of Selected Medicinal Plants from Saurashtra Region, Gujarat.Int.J.Curr.Microbiol.App.Sci. 8(5): 1686-1698. doi: https://doi.org/10.20546/ijcmas.2019.805.195