Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(5): 1225-1233
DOI: https://doi.org/10.20546/ijcmas.2019.805.139


Patho-morphological and Genotoxic Changes in Induced Aflatoxicosis in White Pekin Ducks (Anas platyrhynchos domesticus)
Imran Ali, S.K. Panda*, S. Pati, A.P. Acharya, S.K. Mishra1, G.R. Jena2, G.P. Mohanty3, L. Mohanty, S. Das and D. Kumar1
1ICAR Regional Centre, Central Avian Research Institute,
2Department of Clinical Medicine,
3Department of Livestock Production Management , Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Odisha University of Agriculture and Technology, Bhubaneswar, India
*Corresponding author
Abstract:

The present study attempts to analyze gross and microscopic changes in tissues and genotoxic assessment in bone marrow cells in ducks induced with aflatoxin B1.The study was carried out in 120 nos. of white Pekin ducklings. Ducklings were reared under standard managemental system with ad libitum feed and water etc. for a period of 8thweeks.Aflatoxin B1 added to the feed with different proportion at the dose rate of 6ppb, 12ppb, 24 ppb, &48ppb through premix which were fed to the ducklings of Group 2, 3, 4, 5 respectively, after 3 days with Group 1 as control group. There was a significantly higher chromosomal aberration and micronuclei and lower polychromatic erythrocytes (PCE) in ducks fed with 48 ppb. Grossly liver was enlarged, pale, soft and friable with marked congestion in 48 ppbAFB1. Marked enlargement with reticulation of kidney was evident in group fed with 48 ppb. Bursa was edematous and bursal folds were mildly congested where asthymus was enlarged and pale with petechial. Intestinal wall was slightly thickened with catarrhal exudates and some cases reddish tinged catarrhal exudates in the lumen. Microscopically, at 48 ppb, liver revealed vacuolar degeneration of hepatocytes and mild sinusoidal congestion and focal necrotic area. There was tubular degeneration along with interstitial congestion and desquamated tubular lining epithelial cells in kidney. Lymphoid depletion was evident in bursa of Fabricius and thymus. Toxicopathological effect was pronounced at 48 ppb of aflatoxin B1.


Keywords: Aflatoxin B1, Genotoxic, Gross, microscopic, White Pekin duck
Download this article as Download

How to cite this article:

Imran Ali, S.K. Panda, S. Pati, A.P. Acharya, S.K. Mishra, G.R. Jena, G.P. Mohanty, L. Mohanty, S. Das and Kumar, D. 2019. Patho-morphological and Genotoxic Changes in Induced Aflatoxicosis in White Pekin Ducks (Anas platyrhynchos domesticus).Int.J.Curr.Microbiol.App.Sci. 8(5): 1225-1233. doi: https://doi.org/10.20546/ijcmas.2019.805.139