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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(1): 130-142
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.017


Application of Dental Implants Coated with Titanium Nitride: The Experimental Study with Porphyromonas gingivalis Infection
Koutaro Yamazaki, Izumi Mashima, Futoshi Nakazawa, Yasuhiro Nakanishi and Morio Ochi
1Division of Fixed Prosthodontics and Oral Implantology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan
2Postdoctoral Fellow of Japan Society for the Promotion of Science, Tokyo, Japan
3Department of Oral Microbiology, School of dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan
4Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, New York, USA.
*Corresponding author
Abstract:

Dental implants have been effective for oral rehabilitation. Surface modification of implants is reportedly very important in achieving excellent osseointegration. In this study, a titanium nitride (TiN)-coated implant was evaluated using experimental infections in animals for use in dental implants. TiN-coated implants not only have optimal surface roughness to achieve osseointegration, but also have antimicrobial activity against Porphyromonas gingivalis, which is a pathogen in peri-implantitis. The present study demonstrated that TiN-coated implants showed less P. gingivalis surface adhesion and less bone resorption induced by P. gingivalis. In addition, the bone implant contact ratio of TiN-coated implants showed the highest percentage, with significant differences compared to machined, sandblasted, acid-etched, and radiofrequency magnetron sputter hydroxyapatite-coated surface modifications, even with P. gingivalis infection. This was the first report to demonstrate that TiN-coated implants were excellent for inducing osseointegration and inhibiting P. gingivalis infection using a simplified animal model.


Keywords: Osseointegration, Peri-implant infection(s), Porphyromonas gingivalis, Infectious disease(s),Oral Rehabilitation.
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How to cite this article:

Koutaro Yamazaki, Izumi Mashima, Futoshi Nakazawa, Yasuhiro Nakanishi, Morio Ochi. 2017. Application of Dental Implants Coated with Titanium Nitride: The Experimental Study with Porphyromonas gingivalis Infection.Int.J.Curr.Microbiol.App.Sci. 6(1): 130-142. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.017