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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(1): 36-41
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.005


Seroprevalence and Recent Trends of Dengue in a Rural Area in South India
Ruby Thomas* and K. Shilpa
Department of Microbiology, Akash Institute of Medical Sciences and Research Center Prasannahalli road, Devanahalli, Bengaluru rural-562110, India
*Corresponding author
Abstract:

Dengue is the most critical arthropod borne viral infection and a major public health concern globally in recent years infecting about 50 million people each year. Dengue infected patients present with symptoms varying from mild fever to life threatening shock. Associated thrombo cytopaenia is a hall mark of a life threatening dengue infection. A platelet count of less than 100,000/µl is a diagnostic criteria for dengue haemorrhagic fever (DHF) as per World Health Organization (WHO) guidelines, 2015. Thrombocytopaenia can be seen in both dengue fever (DF) and DHF. In this study, a total of 1228 patients both out patients and inpatients of Akash Hospital in Bengaluru rural were screened for dengue infection. A rapid-Immuno chromatographic test, (ICT) SD Bioline Dengue Duo® was used to run all the samples for detection of NS1antigen (nonstructural protein), IgM (immunoglobulin M) and IgG (immunoglobulin G). NS1 antigen is an early diagnostic marker, appears on the first day of fever. All positives were confirmed by using Bhat Bioscan® Dengue rapid test kit also detects NS1antigen, IgM and IgG. Out of 1228 samples 324 samples were seropositive. Platelet counts were performed on whole blood on these seropositive patients using Sysmex XS 800i automated haematology analyser. Among the 324 seropositive patients, 17(5.24%) had severe thrombocytopaenia, 109 (33.64%) were showing moderately low platelet count, 93(28.70%) with a borderline count and 105 (32.40%) had a normal platelet count.


Keywords: Dengue,Prevalence, seasonal variation, seropositivity, thrombocytopaenia.
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How to cite this article:

Ruby Thomas and Shilpa, K. 2017. Seroprevalence and Recent Trends of Dengue in a Rural Area in South India.Int.J.Curr.Microbiol.App.Sci. 6(1): 36-41. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.005