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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(4): 1398-1405
DOI: https://doi.org/10.20546/ijcmas.2019.804.162


Effect of Arginine and Vitamin E Supplementation on Delayed Foot Web Reaction to Killed Staphylococcus aureus in Experimental T-2 Mycotoxicosis in Broiler Chicken
B.K. Ramesh1*, H.D. Narayanaswamy2, M.L. Satyanarayana3, Suguna Rao3 and Srikrishna Isloor4
1ICAR-Krishi Vigyan Kendra, Hagari – 583 111, Ballari (Tq), Karnataka, India
2Karnataka Veterinary Animal Fisheries Sciences University, Bidar, Karnataka, India
3Department of Veterinary Pathology
4Department of Veterinary Microbiology, Veterinary College, Hebbal, Bengaluru -560 024, India
*Corresponding author
Abstract:

The toxic effect of different dietary levels of T-2 toxin on cell-mediated arm of immune system was assessed by eliciting delayed foot web reaction (DFWR) in broiler chicken. The nutritional immunomodulation using arginine (ARG) [22 g/kg] and vitamin E (VE) [80 mg/kg] supplementation was attempted. A total of 144 day old commercial broiler chicks were randomly divided into six groups. The first four groups received 0.0 (Control-Group I), 0.25ppm (Group II), 0.50ppm (Group III) and 1ppm (Group IV) of dietary T-2 toxin. The ARG and VE combination was supplemented in the diet of birds fed either ‘0’ (Group V) or 1ppm (Group VI) of T-2 toxin. The test diets were fed for 0-28 days. The birds were sensitized twice on days 14 and 21 with killed S. aureus antigen and challenged intradermally in toe web on day 28. DFWR was measured at 0, 6, 24, and 48h post challenge. The foot web thickness peaked at 24h post challenge. A significant (P≤0.05) reduction in DFWR was observed in birds fed with 1 ppm of T-2 toxin compared to birds in control as well as ARG and VE supplemented groups. At 0.25 and 0.5 ppm of T-2 toxin, the DFWR was similar to control. The DTH reaction to S. aureus antigen in birds fed 1 ppm of T-2 toxin and supplemented with ARG and VE was similar to control birds. ARG and VE complemented each other to offer immunoprotection to birds that received immunotoxicant T-2 toxin in their diet.


Keywords: Broiler chicken, T-2 Toxin, Arginine, Vitamin E, DTH response, Immunomodulation
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How to cite this article:

Ramesh, B.K., H.D. Narayanaswamy, M.L. Satyanarayana, Suguna Rao and Srikrishna Isloor. 2019. Effect of Arginine and Vitamin E Supplementation on Delayed Foot Web Reaction to Killed Staphylococcus aureus in Experimental T-2 Mycotoxicosis in Broiler Chicken.Int.J.Curr.Microbiol.App.Sci. 8(4): 1398-1405. doi: https://doi.org/10.20546/ijcmas.2019.804.162