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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(3): 2009-2019
DOI: https://doi.org/10.20546/ijcmas.2019.803.239


Comparative Study of Antimicrobial Activity of Betel leaf Extract and Antibiotics against Selected Bacterial Pathogens
Ayiman Abdullah Ali Almahdi* and Yashab Kumar
Department of Industrial Microbiology, SHUATS, Allahabad-211007, (U.P) India
*Corresponding author
Abstract:

The antibacterial activity of Betel leaf was studied to screen their ability to inhibit the growth of bacterial pathogens i.e. E. coli, B. cereus, P. aeruginosa and S. typhi. The organisms were subjected to antibiotic sensitivity towards, Ampicillin, Chloramphenicol, Penicillin, Rifampicin, Gentamycin, Tetracycline, Ciprofloxacin, Norfloxacin, Kanamycin, Azithromycin, Ceftazidine, Amikacin, Ofloxacin, Vancomycin and Teicoplanin. S.typhi was the most susceptible organism towards all the tested antibiotics. E. coli, B. cereus and P. aeruginosa were multidrug resistant organisms. The organisms were tested for susceptibility against the Betel leaf using agar well extract diffusion method Methanolic extract of Betel Leaf was found most potent and effective against all the test organisms. Methanol extract of Betel leaf was then subjected to MIC and MBC value determination which showed lowest MIC and MBC value of Betel leaf for S. typhi at 0.1µl/ml and 0.2µl/ml and highest for P. aeruginosa at 12.8 µl/ml and 6.4 µl/ml respectively. The study proves that the methanol extract of betel leaf can be employed effectively to treat the hospital and community acquired infections caused by E. coli, B. cereus, P. aeruginosa, and S. typhi.


Keywords: Extracts, antimicrobial activity, MDR, antibiotics susceptibility, MIC and MBC, E.coli, B.cereus, P.aeruginosa, and S.typhi
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How to cite this article:

Ayiman Abdullah Ali Almahdi and Yashab Kumar. 2019. Comparative Study of Antimicrobial Activity of Betel leaf Extract and Antibiotics against Selected Bacterial Pathogens.Int.J.Curr.Microbiol.App.Sci. 8(3): 2009-2019. doi: https://doi.org/10.20546/ijcmas.2019.803.239