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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 8, Issue:3, March, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(3): 1751-1759
DOI: https://doi.org/10.20546/ijcmas.2019.803.205


Heamatological Studies on Sida Rhombifolia Ethanolic Leaf Extract of Micronor Induced Infertility in Female Rats
R.U. Ukpanukpong1*, R.N. Uyabeme2, F.D. Adebiyi4, D.I. Basiru2, B.S. Akinfesola2 and P.O. Aigbadumah3
1Department of Biochemistry, University of Calabar, Nigeria
2 Department of Chemical Sciences, Biochemistry Unit, Joseph Ayo Babalola University,Osun State, Nigeria
3Faculty of Medical Sciences, University of Jos, Nigeria
4Department of Cell Biology and Genetics, University of Lagos, Nigeria
*Corresponding author
Abstract:

The research investigated the heamatological indices of Sida rhombifolia ethanolic leaf extract on micronor induced infertility in female rats. Sida rhombifolia is a shrub from the family of Malvaceae. Forty eight (48) female albino rats were randomly placed into six (6) study groups of eight (8) rats each and designated as; positive control group (PC) placed on distill water and normal feeds, micronor control group (MC) induced with micronor but not treated with Sida rhombifolia, Sida rhombifolia control group (SRC), (SRM1, SRM2, SRM3) induced with micronor and treated with ethanolic leaf extract of Sida rhombifolia at concentrations of 100mg/kg, 200 mg/kg and 400 mg/kg body weight respectively for 14 days. Animals treated with 200mg/kg and 400mg/kg Sida rhombifolia ethanolic leaf extract showed a significant increase in white blood cell count activity and neutrophil concentration compared to the micronor control. There was also a significant increase (P<0.05) in the red blood cell counts of the extract treated group compared to the positive control. The extract was found to be non-toxic as seen in the extract fed normal rats. Findings depicts that ethanolic leaf extract of Sida rhombifolia possessed some hematopoitic effect on micronor induced infertility in female rats.


Keywords: Body Weight Indices, Weight Blood cell Count, Red Blood Cell Counts Neutrophil and Mean Corpuscular Haemoglobin Concentration

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How to cite this article:

Ukpanukpong, R.U., R.N. Uyabeme, F.D. Adebiyi, D.I. Basiru, B.S. Akinfesola and Aigbadumah, P.O. 2019. Heamatological Studies on Sida Rhombifolia Ethanolic Leaf Extract of Micronor Induced Infertility in Female Rats.Int.J.Curr.Microbiol.App.Sci. 8(3): 1751-1759. doi: https://doi.org/10.20546/ijcmas.2019.803.205
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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