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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(12): 609-613
DOI: http://dx.doi.org/10.20546/ijcmas.2016.512.066


Antifungal Susceptibility of Candiduria Isolates by E Test Method
R. Deepa*
Travancore Medical College, Kollam, India
*Corresponding author
Abstract:

Candida species other than Candida albicans have now emerged as an important cause of UTI and some of which exhibit reduced susceptibility to commonly used antifungal agents. It causes urinary tract infections in healthy individuals, but common in hospital settings. The aim of this study was to investigate species distribution and antifungal susceptibility profile of Candida species causing candiduria. The present study determined the Antifungal susceptibilities of the Candida isolates from urine against Fluconazole and Itraconazole and Ketoconazole by E-test according to the CLSI reference method M27-S4. Glucose methylene Mueller- Hinton agar (GM-MH) was used as the test medium. Out of 84 isolates of C. albicans 23(27%) showed maximum resistance to fluconazole followed by ketoconazole. 18(21%). Fluconazole resistance was more in C. tropicalis (11) followed by C.albicans (9). Resistance to ketoconazole was common in C. tropicalis (7). Itraconazole resistance was also higher in C. tropicalis (7). Therefore, it can be concluded that non Candida albicans have emerged as an important cause of urinary tract infections. Susceptibility results shows that there is emerging fungal resistance to azoles particularly fluconazole and new generation triazoles.


Keywords: Candiduria,Candida albicans,Non Candida albicans, Antifungal susceptibility, Epsilometer-test, Minimum inhibitory concentration
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How to cite this article:

Deepa, R., 2016. Antifungal Susceptibility of Candiduria Isolates by E Test Method.Int.J.Curr.Microbiol.App.Sci. 5(12): 609-613. doi: http://dx.doi.org/10.20546/ijcmas.2016.512.066