Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(3): 472-475
DOI: https://doi.org/10.20546/ijcmas.2019.803.059


Group A Streptococcal Carriage in Children with ADHD: Antibiotic Resistance and Associated ASO Levels
Eunice Swarna Jacob*, S. Matheskumar and Rishab Bharadwaj
Department of Microbiology, Thanjavur Medical College, Chennai, India
*Corresponding author
Abstract:

Acute pharyngitis is a common illness of childhood most frequently associated with Group A Streptococcus (GAS) and carrier state quiet often remains undiagnosed in children with attention deficit hyperactivity disorder. This prospective study was undertaken to assess the burden of GAS in children with attention deficit hyperactivity disorder attending pediatric clinics in a tertiary care centre at Chennai. Throat swabs were obtained for culture from 50 ADHD children aged 5 – 15 years with symptoms of sore throat and 50 from apparently asymptomatic children with ADHD. Beta hemolytic streptococcal isolates were isolated and serogrouped and subjected to antibiotic susceptibility testing as per CLSI standards. Blood samples were collected from all 100 children to determine elevated ASO levels. 24 children of the symptomatic study group were positive for beta hemolytic streptococci. Asymptomatic carriage of GAS was 28%. Antibiotic resistance to erythromycin, azithromycin and ofloxacin was high. All strains were sensitive to Penicillin. Nineteen children had elevated ASO titre levels. Periodic surveillance is mandatory to prevent the spread of GAS carriage in children with ADHD. Multidrug resistant phenotypes are emerging. Regular monitoring of drug resistance will serve as a valuable tool in preventing periodic outbreak in the community.


Keywords: GAS – Resistance-Macrolides – ASO
Download this article as Download

How to cite this article:

Eunice Swarna Jacob, S. Matheskumar and Rishab Bharadwaj. 2019. Group A Streptococcal Carriage in Children with ADHD: Antibiotic Resistance and Associated ASO Levels.Int.J.Curr.Microbiol.App.Sci. 8(3): 472-475. doi: https://doi.org/10.20546/ijcmas.2019.803.059