Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(2): 1002-1010
DOI: https://doi.org/10.20546/ijcmas.2019.802.116


Plant Tissue Culture Technology: Sustainable Option for Mining High Value Pharmaceutical Compounds
M.K. Tripathi, Nishi Mishra, Sushma Tiwari*, Chitralekha Shyam, Sonali Singh and Ashok Ahuja
Department of Plant Molecular Biology & Biotechnology, College of Agriculture, RVSKVV, Gwalior 474002, MP, India
*Corresponding author
Abstract:

Production of secondary metabolites from plant tissue culture has emerged as a promising and feasible option attracting the attention of scientists worldwide. Plant cell, tissue and organ cultures offer an attractive alternative for homogeneous, controlled production of secondary metabolites, throughout the year, especially when we take commercial demand into account. They not only facilitate the de novo synthesis of novel compounds, but also are able to produce compounds sometimes even in higher amounts than the intact plants. Many biotechnological strategies have been experimented for enhanced production of secondary metabolites from medicinal plants. Some of these include screening of high yielding cell lines, media modification, precursor feeding, elicitation, large scale cultivation in bioreactor system, hairy root culture, plant cell immobilization, biotransformation and many others. Some of the recent developments such as metabolic engineering of whole plants and plant cell cultures have been established as effective tools to increase metabolites yield. The use of genetic engineering tools and elucidation of pathways for secondary metabolism has provided the basis for the production of commercially acceptable levels of product. In view of commercial importance of the secondary metabolites as high value pharmaceutical compounds in recent years resulted in a immersive interest, in secondary metabolism, and particularly in the possibility to alter the production of bioactive plant metabolites by utilizing biotechnological tools. The plant cell culture technology provides sustainable option for production of plant pharmaceuticals and could be used for the large-scale production of metabolites.


Keywords: Tissue culture, Pharmaceutical compounds, Secondary metabolism
Download this article as Download

How to cite this article:

Tripathi, M.K., Nishi Mishra, Sushma Tiwari, Chitralekha Shyam, Sonali Singh and Ashok Ahuja. 2019. Plant Tissue Culture Technology: Sustainable Option for Mining High Value Pharmaceutical Compounds.Int.J.Curr.Microbiol.App.Sci. 8(2): 1002-1010. doi: https://doi.org/10.20546/ijcmas.2019.802.116