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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(2): 125-130
DOI: https://doi.org/10.20546/ijcmas.2019.802.015


Acute Effect of Intravenous Ethanol on Electrocardiogram of New Zealand White Rabbits
Jafrin Ara Ahmed1, Nawab Nashiruddullah2, Juneet Kour1 and Dibyendu Chakraborty3*
1Division of Veterinary Physiology and Biochemistry
2Division of Veterinary Pathology
3Division of Animal Genetics & Breeding, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Jammu, R.S. Pura, Jammu-181102, India
*Corresponding author
Abstract:

The present study was undertaken to study the effects of intra-venous (i.v.) ethanol (25%, 50% and 100%) on Electrocardiogram of New Zealand White rabbits. Twelve healthy and clinically normal New Zealand White rabbits of either sex, weighing between 2-3 kg and aged between 1-2 years were selected for the present study. 1 ml of ethanol (25%, 50% and 100%) was injected i.v. in the ear vein of the rabbit and ECG recordings were taken for 50 minutes. Rabbits exhibited a significant decrease in heart rate following the injection of 25% and 50% ethanol and the heart rate remained significantly (P<0.01) depressed for a period of 30 minutes. Low P-wave amplitude was observed. QRS amplitudes have increased significantly in 25% and 50% ethanol treated group. Increased QRS voltage, and prolonged ventricular activation time, likely represents left ventricular hypertrophy. But QRS amplitude has decreased significantly in 100% ethanol treatment. T wave amplitudes significantly increase in 25% and 50% treatment group and decrease in 100% treatment group. QT interval indicating the total duration of electrical activity in the ventricles was significantly increased compared with that of control group (50% treated group).


Keywords: Electrocardiogram, Ethanol, New Zealand White rabbit
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How to cite this article:

Jafrin Ara Ahmed, Nawab Nashiruddullah, Juneet Kour and Dibyendu Chakraborty. 2019. Acute Effect of Intravenous Ethanol on Electrocardiogram of New Zealand White Rabbits.Int.J.Curr.Microbiol.App.Sci. 8(2): 125-130. doi: https://doi.org/10.20546/ijcmas.2019.802.015