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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(1): 1369-1376
DOI: https://doi.org/10.20546/ijcmas.2019.801.145


Detection of Extended Spectrum Betalactamases (ESBLs) Producing Enterobacteriaceae from Clinical Samples of Pus
K.R. Shobha Medegar, Y.K. Harshika* and Asha B. Patil
Department of Microbiology Karnataka Institute of Medical Sciences, Vidyanagar, Hubli – 580022, India
*Corresponding author
Abstract:

Extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae has tremendously increased worldwide and it is one of the most common causes of morbidity and mortality associated with hospital-acquired infections. This could be attributed to association of multi drug resistance in ESBL producing isolates. Therefore, in the present study, an attempt was made to know the rate of ESBL producing Enterobacteriaceae and to know their antibiogram at Dr. B.R. Ambedkar Medical College. Bangalore. All the patients with signs and symptoms suggestive of abscess, wound infection, otitis media were included in the study. Pus samples from these patients were processed with standard microbiological procedures and the isolates were screened for ESBL production by Double disk synergy method. Out of 100 isolates, 19 isolates were ESBL producers. The most common ESBL producers were E. coli followed by Klebsiella, Citrobacter and Enterobacter. Majority of ESBL producers showed resistance to Ampicillin, Amoxyclav, cotrimoxazole and Amikacin. The production of ESBLs by clinically important isolates is emerging as a wide spread problem in our set up. Hence, routine detection, appropriate infection control measures are needed to stem the spread of this emerging form of resistance.


Keywords: Enterobacteriaceae, Drug resistance, ESBL, DDST, Pus
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How to cite this article:

Shobha Medegar, K.R., Y.K. Harshika and Asha B. Patil. 2019. Detection of Extended Spectrum Betalactamases (ESBLs) Producing Enterobacteriaceae from Clinical Samples of Pus.Int.J.Curr.Microbiol.App.Sci. 8(1): 1369-1376. doi: https://doi.org/10.20546/ijcmas.2019.801.145