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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(1): 22-27
DOI: https://doi.org/10.20546/ijcmas.2019.801.003


Changing Trends in Resistance Pattern of Methicillin Resistant Staphylococcus aureus in Burn Patients
S.R. More, Tadvi Khan Saleha Kauser*, S.K. Kandle and V.S. Rathod
Department of Microbiology, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India
*Corresponding author
Abstract:

Historically, S. aureus has been one of the most common pathogens which caused pyogenic local and systemic infections in both hospitals and community. Methicillin resistance in Staphylococcus aureus is associated with multidrug resistance, an aggressive course, increased mortality and morbidity in both community and health care facilities. This cross sectional study was carried out in a 70 burn patients from May 2016 to July 2018 at DR.S.C.G.M.C, Nanded India. Swabs were taken and cultured for bacterial isolation and identification following standard operative procedures. Antimicrobial susceptibility was performed by Kirby Bauer’s disc diffusion method which used a 30µg Cefoxitin disc according to CLSI 2018 guidelines. MRSA isolates showed high resistance to ciprofloxacin (76.4%), gentamicin (64.7%) as compared to other drugs. High prevalence of Ciprofloxacin resistance was detected. Multi resistant MRSA with a ‘D’ test positive was 79%. All MRSA isolates were sensitive to Vancomycin, Linezolid. MRSA had displayed increase in resistance to most antibiotics with ‘D’ test positive in recent years. Taking into consideration the prevalence of multidrug-resistance in MRSA, resistance patterns should be evaluated periodically and antibiotic therapy should be guided by susceptibility testing.


Keywords: Trends, Methicillin Resistant Staphylococcus aureus, Burn patients
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How to cite this article:

More, S.R., Tadvi Khan Saleha Kauser, S.K. Kandle and Rathod, V.S. 2019. Changing Trends in Resistance Pattern of Methicillin Resistant Staphylococcus aureus in Burn Patients.Int.J.Curr.Microbiol.App.Sci. 8(1): 22-27. doi: https://doi.org/10.20546/ijcmas.2019.801.003