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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The aim of the research was to study the microbial landscape of sputum of patients with occupational COPD with different clinical phenotypes and comorbidity. The objective of the study was 374 patients with chronic occupational respiratory pathology. A comparative analysis of sputum microbiocenosis was performed in all the patients of the groups (on the whole, there were 616 samples of sputum gathered from 374 patients). Microorganisms could be detected statistically more often in patients with the combination of COPD and DM (p<0.001). A bacterial monoculture statistically more often was detected in patients with chronic non obstructive bronchitis and COPD – non exacebrator groups (p<0.001). Microbial associations were detected significantly more often among the patients who had COPD-Asthma overlap and DM II (p<0.001). The conspicuous quantitative and qualitative changes of respiratory tract microbiom of patients with occupational COPD are observed only if they have associated DM II.