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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(12): 3178-3182
DOI: https://doi.org/10.20546/ijcmas.2018.712.366


High Level Aminoglycoside Resistance (HLAR) in Enterococcus Species Isolated from Various Clinical Specimens
Sheetal Sharma1*, Prasanna Gupta2 and Suman Rishi2
1Medical Microbiology
2Department of Microbiology, National Institute of Medical Sciences & Research Jaipur, NIMS University (Rajasthan) India- 303121
*Corresponding author
Abstract:

Enterococci are the most aerobic and facultative anaerobe, gram positive cocci. They constitute a part of normal intestinal flora. However they also occupy other sites such as oral cavity, skin etc. Enterococci, which earlier considered as low grade pathogens, has now emerged as one of the most important nosocomial pathogens worldwide and are associated with high mortality. Study was carried out in the Department of Microbiology, National Institute of Medical Sciences & Research Jaipur (India) between December 2016 and December 2017. The isolated Enetrococci are then tested for routine antibiotics sensitivity by disc diffusion method including High level Gentamicin and Streptomycin disc. Further confirmation of High level Gentamicin and Streptomycin resistance by E-test (MIC). We consider MIC test as gold slandered method. A total 110 Enterococcus isolates are obtained from various clinical specimens such as Blood, Urine, Pus. Among 110 Enterococcus species, 78 species are Enterococcus faecalis and 32 species are Enterococcus faecium. Out of 110 Enterococcus isolates 36 (32.7%) are resistant to High level Gentamicin and 24 (21.8%) are resistant to High level streptomycin by disc diffusion method and by E-test High level Gentamicin was 41 (37.2%) and High level streptomycin was 27 (24.5%) found. Prevalence of HLAR is high and could be a serious problem in hospital setup, screening for high level aminoglycoside resistance must be included in routine antibiotic susceptibility reporting for Enterococcal isolates.


Keywords: High level aminoglycoside resistance, Enterococcus Infections, E-test
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How to cite this article:

Sheetal Sharma, Prasanna Gupta and Suman Rishi. 2018. High Level Aminoglycoside Resistance (HLAR) in Enterococcus Species Isolated from Various Clinical Specimens.Int.J.Curr.Microbiol.App.Sci. 7(12): 3178-3182. doi: https://doi.org/10.20546/ijcmas.2018.712.366