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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(12): 2488-2494
DOI: https://doi.org/10.20546/ijcmas.2018.712.283


Adverse Effects of Chemotherapy with Doxorubicin and Vincristine in Canine Transmissible Venereal Tumour
Anup Yadav1, Praveen Kumar2*, Lokesh3, Ashwani Kumar2, Pankaj Kumar4, Rajendra Yadav5, N.S. Bugaliaand R.P. Diwakar6
1Department of Veterinary Gynaecology and Obstetrics
2Department of Veterinary Medicine
3Department of Veterinary Surgery, (LUVAS, Hisar), India
4Disease Investigation Laboratory, Rohtak (LUVAS, Hisar), India
5RVDEC, Mahendergarh (LUVAS, Hisar), India
6Department of Veterinary Microbiology, C.V.Sc&A.H., N.D.U.A&T., Kumarganj, Faizabad (U.P), India
*Corresponding author
Abstract:

Present study was conducted at TVCC, LUVAS, Hisar on Twenty-four dogs irrespective of age, breed, sex affected with canine transmissible venereal tumour (TVT). Affected dogs were divided equally into three groups on the basis of treatment with chemotherapeutic drugs viz. vincristine therapy (Group I) and doxorubicin therapy (Group II and III). Vomition, diarrhea, alopecia, allergic nodules and stomatitis were adverse effects of chemotherapy in TVT affected dogs. Maximum adverse effects of chemotherapy were recorded with vincristine therapy (Group I), followed by 14 days interval doxorubicin therapy (Group II)and minimum adverse effects with 21 days interval doxorubicin (Group III).


Keywords: Transmissible Venereal Tumour (TVT), Doxorubicin and Vincristine
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How to cite this article:

Anup Yadav, Praveen Kumar, Lokesh, Ashwani Kumar, Pankaj Kumar, Rajendra Yadav, N.S. Bugalia and Diwakar, R.P. 2018. Adverse Effects of Chemotherapy with Doxorubicin and Vincristine in Canine Transmissible Venereal Tumour.Int.J.Curr.Microbiol.App.Sci. 7(12): 2488-2494. doi: https://doi.org/10.20546/ijcmas.2018.712.283